Cardiovascular Precision Medicine in the Genomics Era
Sign Up to like & getrecommendations! Published in 2018 at "JACC: Basic to Translational Science"
DOI: 10.1016/j.jacbts.2018.01.003
Abstract: Summary Precision medicine strives to delineate disease using multiple data sources—from genomics to digital health metrics—in order to be more precise and accurate in our diagnoses, definitions, and treatments of disease subtypes. By defining disease… read more here.
Keywords: medicine; precision medicine; medicine genomics; cardiovascular precision ... See more keywords
Constructing linkage maps in the genomics era with MapDisto 2.0
Sign Up to like & getrecommendations! Published in 2017 at "Bioinformatics"
DOI: 10.1093/bioinformatics/btx177
Abstract: Motivation: Genotyping by sequencing (GBS) generates datasets that are challenging to handle by current genetic mapping software with graphical interface. Geneticists need new user‐friendly computer programs that can analyze GBS data on desktop computers. This… read more here.
Keywords: constructing linkage; linkage; maps genomics; genomics era ... See more keywords
Malignant Hyperthermia in the Post-Genomics Era: New Perspectives on an Old Concept.
Sign Up to like & getrecommendations! Published in 2018 at "Anesthesiology"
DOI: 10.1097/aln.0000000000001878
Abstract: This article reviews advancements in the genetics of malignant hyperthermia, new technologies and approaches for its diagnosis, and the existing limitations of genetic testing for malignant hyperthermia. It also reviews the various RYR1-related disorders and… read more here.
Keywords: hyperthermia; malignant hyperthermia; era new; hyperthermia post ... See more keywords
Rethinking what constitutes a diagnosis in the genomics era: a critical illness perspective.
Sign Up to like & getrecommendations! Published in 2019 at "Current Opinion in Pediatrics"
DOI: 10.1097/mop.0000000000000754
Abstract: PURPOSE OF REVIEW The purpose of this review is to highlight the significant advances in the testing, interpretation, and diagnosis of genetic abnormalities in critically ill children and to emphasize that pediatric intensivists are uniquely… read more here.
Keywords: diagnosis; genomics era; era critical; rethinking constitutes ... See more keywords
The relevance of pedigrees in the conservation genomics era.
Sign Up to like & getrecommendations! Published in 2021 at "Molecular ecology"
DOI: 10.1111/mec.16192
Abstract: Over the past 50 years conservation genetics has developed a substantive toolbox to inform species management. One of the most long-standing tools available to manage genetics - the pedigree - has been widely used to… read more here.
Keywords: conservation genomics; genetics; conservation; relevance pedigrees ... See more keywords
Post genomics era for orchid research
Sign Up to like & getrecommendations! Published in 2017 at "Botanical Studies"
DOI: 10.1186/s40529-017-0213-7
Abstract: Among 300,000 species in angiosperms, Orchidaceae containing 30,000 species is one of the largest families. Almost every habitats on earth have orchid plants successfully colonized, and it indicates that orchids are among the plants with… read more here.
Keywords: era orchid; orchid research; research post; genomics era ... See more keywords
Computational Genomics in the Era of Precision Medicine: Applications to Variant Analysis and Gene Therapy
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Personalized Medicine"
DOI: 10.3390/jpm12020175
Abstract: Rapid methodological advances in statistical and computational genomics have enabled researchers to better identify and interpret both rare and common variants responsible for complex human diseases. As we continue to see an expansion of these… read more here.
Keywords: therapy computational; genomics era; gene therapy; computational genomics ... See more keywords