Functional Characterization of Structural Genomics Proteins in the Crotonase Superfamily.
Sign Up to like & getrecommendations! Published in 2022 at "ACS chemical biology"
DOI: 10.1021/acschembio.1c00842
Abstract: Members of the Crotonase superfamily, a mechanistically diverse family of proteins that share a conserved quaternary structure, can often catalyze more than one reaction. However, the spectrum of activity for its members has not been… read more here.
Keywords: hydrolase activity; structural genomics; crotonase superfamily; genomics proteins ... See more keywords
Genomics 2 Proteins portal: a resource and discovery tool for linking genetic screening outputs to protein sequences and structures
Sign Up to like & getrecommendations! Published in 2024 at "Nature Methods"
DOI: 10.1038/s41592-024-02409-0
Abstract: Recent advances in AI-based methods have revolutionized the field of structural biology. Concomitantly, high-throughput sequencing and functional genomics have generated genetic variants at an unprecedented scale. However, efficient tools and resources are needed to link… read more here.
Keywords: genomics proteins; discovery tool; protein sequences; proteins portal ... See more keywords