Advances in technologies for 3D genomics research
Sign Up to like & getrecommendations! Published in 2020 at "Science China Life Sciences"
DOI: 10.1007/s11427-019-1704-2
Abstract: The spatial structure of the orderly organized chromatin in the nucleus has important roles in maintaining normal cell function and in regulation of gene expression, and the high-throughput Hi-C and ChIA-PET methods have been widely… read more here.
Keywords: technologies genomics; research; genomics research; advances technologies ... See more keywords
Conceptualization of utility in translational clinical genomics research.
Sign Up to like & getrecommendations! Published in 2021 at "American journal of human genetics"
DOI: 10.1016/j.ajhg.2021.08.013
Abstract: Prior to integration into clinical care, a novel medical innovation is typically assessed in terms of its balance of benefits and risks, often referred to as utility. Members of multidisciplinary research teams may conceptualize and… read more here.
Keywords: research; utility; genomics research; conceptualization utility ... See more keywords
39 Using artificial intelligence to analyze horse gait parameters for genomics research in musculoskeletal traits
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Equine Veterinary Science"
DOI: 10.1016/j.jevs.2021.103502
Abstract: Arguably the most important factors considered when assessing elite performance horses, traits of “lameness susceptibility” and “gait quality” lack objective and quantitative measures. Popular qualitative approaches to determine lameness or gait quality do not provide… read more here.
Keywords: artificial intelligence; horse; genomics research; gait ... See more keywords
Rice Functional Genomics Research: Past Decade and Future.
Sign Up to like & getrecommendations! Published in 2018 at "Molecular plant"
DOI: 10.1016/j.molp.2018.01.007
Abstract: Rice (Oryza sativa) is a major staple food crop for more than 3.5 billion people worldwide. Understanding the regulatory mechanisms of complex agronomic traits in rice is critical for global food security. Rice is also… read more here.
Keywords: research past; functional genomics; genomics research; rice functional ... See more keywords
Embracing an "African Ethos" to facilitate African immigrants participation in medical genetics and genomics research.
Sign Up to like & getrecommendations! Published in 2017 at "Nursing outlook"
DOI: 10.1016/j.outlook.2016.08.001
Abstract: BACKGROUND Limited published research exists on perceptions and potentials for black African immigrants' participation in medical genetics and genomics research. PURPOSE This study explores the inclination and disinclination of African immigrants to be involved in genetics… read more here.
Keywords: participation; african immigrants; genetics; genomics research ... See more keywords
The approach to predictive medicine that is taking genomics research by storm
Sign Up to like & getrecommendations! Published in 2018 at "Nature"
DOI: 10.1038/d41586-018-06956-3
Abstract: Polygenic risk scores represent a giant leap for gene-based diagnostic tests. Here’s why they’re still so controversial.Polygenic risk scores represent a giant leap for gene-based diagnostic tests. Here’s why they’re still so controversial. read more here.
Keywords: taking genomics; medicine; medicine taking; predictive medicine ... See more keywords
Design considerations for workflow management systems use in production genomics research and the clinic
Sign Up to like & getrecommendations! Published in 2021 at "Scientific Reports"
DOI: 10.1038/s41598-021-99288-8
Abstract: The changing landscape of genomics research and clinical practice has created a need for computational pipelines capable of efficiently orchestrating complex analysis stages while handling large volumes of data across heterogeneous computational environments. Workflow Management… read more here.
Keywords: management systems; research; workflow management; genomics research ... See more keywords
Mapping the Landscape of Indian Genomics Research: A Scientometric Analysis.
Sign Up to like & getrecommendations! Published in 2023 at "Rejuvenation research"
DOI: 10.1089/rej.2023.0003
Abstract: This Scientometric study aimed to provide state-of-the-art information on research growth and trends, areas of potential growth and development in genomics in India, and identify the key players (organizations or institutions, and funding agencies). It… read more here.
Keywords: genomics research; indian genomics; research; landscape indian ... See more keywords
Five Priorities of African Genomics Research: The Next Frontier.
Sign Up to like & getrecommendations! Published in 2022 at "Annual review of genomics and human genetics"
DOI: 10.1146/annurev-genom-111521-102452
Abstract: To embrace the prospects of accurately diagnosing thousands of monogenic conditions, predicting disease risks for complex traits or diseases, tailoring treatment to individuals' pharmacogenetic profiles, and potentially curing some diseases, research into African genomic variation… read more here.
Keywords: genomics research; five priorities; african genomics; priorities african ... See more keywords
Sources of bias in genomics research of oral and dental traits.
Sign Up to like & getrecommendations! Published in 2020 at "Community dental health"
DOI: 10.1922/cdh_specialissue_divaris05
Abstract: Evidence regarding the genomic basis of oral/dental traits and diseases is a fundamental pillar of the emerging notion of precision health. During the last decade, technological advances have improved the feasibility and affordability of conducting… read more here.
Keywords: sources bias; dental traits; oral dental; health ... See more keywords
Opportunities and Challenges in Functional Genomics Research in Osteoporosis: Report From a Workshop Held by the Causes Working Group of the Osteoporosis and Bone Research Academy of the Royal Osteoporosis Society on October 5th 2020
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Endocrinology"
DOI: 10.3389/fendo.2020.630875
Abstract: The discovery that sclerostin is the defective protein underlying the rare heritable bone mass disorder, sclerosteosis, ultimately led to development of anti-sclerostin antibodies as a new treatment for osteoporosis. In the era of large scale… read more here.
Keywords: research; functional genomics; genetic signals; genomics research ... See more keywords