Abstract LB-116: Functional genomics screening using LentiArray™ CRISPR libraries and CellSensor™ assays
Sign Up to like & getrecommendations! Published in 2017 at "Cancer Research"
DOI: 10.1158/1538-7445.am2017-lb-116
Abstract: Identifying and validating targets that underlie disease mechanisms and can be addressed to provide efficacious therapies remains a significant challenge in the drug discovery and development process. Use of siRNA and shRNA to knock-down RNA… read more here.
Keywords: knock; genomics screening; crispr; lentiarray crispr ... See more keywords
MasterPATH: network analysis of functional genomics screening data
Sign Up to like & getrecommendations! Published in 2020 at "BMC Genomics"
DOI: 10.1186/s12864-020-07047-2
Abstract: Background Functional genomics employs several experimental approaches to investigate gene functions. High-throughput techniques, such as loss-of-function screening and transcriptome profiling, allow to identify lists of genes potentially involved in biological processes of interest (so called… read more here.
Keywords: screening data; genomics screening; functional genomics; network analysis ... See more keywords