The role of ABCA7 in Alzheimer’s disease: evidence from genomics, transcriptomics and methylomics
Sign Up to like & getrecommendations! Published in 2019 at "Acta Neuropathologica"
DOI: 10.1007/s00401-019-01994-1
Abstract: Genome-wide association studies (GWAS) originally identified ATP-binding cassette, sub-family A, member 7 (ABCA7), as a novel risk gene of Alzheimer’s disease (AD). Since then, accumulating evidence from in vitro, in vivo, and human-based studies has… read more here.
Keywords: alzheimer disease; disease; abca7; evidence ... See more keywords
Genomics and Transcriptomics of the green mussel explain the durability of its byssus
Sign Up to like & getrecommendations! Published in 2021 at "Scientific Reports"
DOI: 10.1038/s41598-021-84948-6
Abstract: Mussels, which occupy important positions in marine ecosystems, attach tightly to underwater substrates using a proteinaceous holdfast known as the byssus, which is tough, durable, and resistant to enzymatic degradation. Although various byssal proteins have… read more here.
Keywords: mussel explain; transcriptomics green; green mussel; byssus ... See more keywords
An overview of bioinformatics, genomics and transcriptomics resources for bryophytes.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of experimental botany"
DOI: 10.1093/jxb/erac052
Abstract: Bryophytes are useful models for the study of plant evolution, development, plant-fungal symbiosis, stress responses and gametogenesis. Additionally, their dominant haploid gametophytic phase makes them great models for functional genomics research, allowing straightforward genome editing… read more here.
Keywords: transcriptomics resources; bioinformatics genomics; resources bryophytes; genomics transcriptomics ... See more keywords
Genomics, transcriptomics and proteomics: enabling insights into social evolution and disease challenges for managed and wild bees
Sign Up to like & getrecommendations! Published in 2017 at "Molecular Ecology"
DOI: 10.1111/mec.13986
Abstract: Globally, there are over 20 000 bee species (Hymenoptera: Apoidea: Anthophila) with a host of biologically fascinating characteristics. Although they have long been studied as models for social evolution, recent challenges to bee health (mainly… read more here.
Keywords: evolution; transcriptomics proteomics; enabling insights; genomics transcriptomics ... See more keywords
Stepwise use of genomics and transcriptomics technologies increases diagnostic yield in Mendelian disorders
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2023.1021920
Abstract: Purpose: Multi-omics offer worthwhile and increasingly accessible technologies to diagnostic laboratories seeking potential second-tier strategies to help patients with unresolved rare diseases, especially patients clinically diagnosed with a rare OMIM (Online Mendelian Inheritance in Man)… read more here.
Keywords: use genomics; stepwise use; diagnosis; transcriptomics technologies ... See more keywords
Pathogenesis of Choledochal Cyst: Insights from Genomics and Transcriptomics
Sign Up to like & getrecommendations! Published in 2022 at "Genes"
DOI: 10.3390/genes13061030
Abstract: Choledochal cysts (CC) is characterized by extra- and/or intra-hepatic b\ile duct dilations. There are two main theories, “pancreaticobiliary maljunction” and “congenital stenosis of bile ducts” proposed for the pathogenesis of CC. Although family cases or… read more here.
Keywords: cyst insights; insights genomics; pathogenesis choledochal; genomics transcriptomics ... See more keywords
Genomics, Transcriptomics, and Proteomics of SSV1 and Related Fusellovirus: A Minireview
Sign Up to like & getrecommendations! Published in 2022 at "Viruses"
DOI: 10.3390/v14102082
Abstract: Saccharolobus spindle-shaped virus 1 (SSV1) was one of the first viruses identified in the archaeal kingdom. Originally isolated from a Japanese species of Saccharolobus back in 1984, it has been extensively used as a model… read more here.
Keywords: transcriptomics proteomics; ssv1 related; related fusellovirus; proteomics ssv1 ... See more keywords