Use of early phenotypic in vivo markers to assess human relevance of an unusual rodent non-genotoxic carcinogen in vitro.
Sign Up to like & getrecommendations! Published in 2017 at "Toxicology"
DOI: 10.1016/j.tox.2017.01.018
Abstract: Foci of altered hepatocytes (FAH) are considered putative, pre-neoplastic lesions that can occur spontaneously in aging rodents, but can also be induced by chemicals or drugs. Progression of FAH to hepatocellular neoplasms has been reported… read more here.
Keywords: genotoxic carcinogen; relevance; non genotoxic; human relevance ... See more keywords
Substantial Evidences Indicate That Inorganic Arsenic Is a Genotoxic Carcinogen: a Review
Sign Up to like & getrecommendations! Published in 2018 at "Toxicological Research"
DOI: 10.5487/tr.2018.34.4.311
Abstract: Arsenic is one of the most toxic environmental toxicants. More than 150 million people worldwide are exposed to arsenic through ground water contamination. It is an exclusive human carcinogen. Although the hallmarks of arsenic toxicity… read more here.
Keywords: arsenic genotoxic; genotoxic carcinogen; inorganic arsenic; substantial evidences ... See more keywords