Mesenchyme-derived factors enhance preneoplastic growth by non-genotoxic carcinogens in rat liver
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DOI: 10.1007/s00204-017-2080-0
Abstract: Many frequently prescribed drugs are non-genotoxic carcinogens (NGC) in rodent liver. Their mode of action and health risks for humans remain to be elucidated. Here, we investigated the impact of two model NGC, the anti-epileptic… read more here.
Keywords: growth; non genotoxic; genotoxic carcinogens; rat liver ... See more keywords
Mode of action-based risk assessment of genotoxic carcinogens
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DOI: 10.1007/s00204-020-02733-2
Abstract: The risk assessment of chemical carcinogens is one major task in toxicology. Even though exposure has been mitigated effectively during the last decades, low levels of carcinogenic substances in food and at the workplace are… read more here.
Keywords: risk; risk assessment; genotoxic carcinogens; genotoxic ... See more keywords