c-Rel dependant Chk2 signalling regulates the DNA damage response limiting hepatocarcinogenesis.
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DOI: 10.1002/hep.32781
Abstract: BACKGROUND AND AIMS Hepatocellular carcinoma (HCC) is a leading cause of cancer-related death. c-Rel, an NF-κB transcription factor family subunit is typically pro-tumourigenic, however, it has recently been reported as a tumour suppressor. Here we… read more here.
Keywords: genotoxic injury; dna damage; rel; damage response ... See more keywords