Quantitative in vitro to in vivo extrapolation of genotoxicity data provides protective estimates of in vivo dose
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DOI: 10.1002/em.22521
Abstract: Genotoxicity assessment is a critical component in the development and evaluation of chemicals. Traditional genotoxicity assays (i.e., mutagenicity, clastogenicity, and aneugenicity) have been limited to dichotomous hazard classification, while other toxicity endpoints are assessed through… read more here.
Keywords: genotoxicity data; genotoxicity; vitro vivo; vivo extrapolation ... See more keywords