Antibacterial Layer‐by‐Layer Films of Poly(acrylic acid)–Gentamicin Complexes with a Combined Burst and Sustainable Release of Gentamicin
Sign Up to like & getrecommendations! Published in 2019 at "Advanced Materials Interfaces"
DOI: 10.1002/admi.201901373
Abstract: The widespread nature of bacterial infections and their increasing resistance to antibiotics has led to the development of antibacterial coatings in multiple medical settings, especially on bone implants.[1] The surface of implants is susceptible to… read more here.
Keywords: release gentamicin; surgery; gentamicin; layer ... See more keywords
Hair cell uptake of gentamicin in the developing mouse utricle
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.30228
Abstract: Intratympanic injection of gentamicin has proven to be an effective therapy for intractable vestibular dysfunction. However, most studies to date have focused on the cochlea, so little is known about the distribution and uptake of… read more here.
Keywords: met channels; gentamicin; hcs; hair ... See more keywords
Gentamicin Has No Significant Adverse Effect on Porcine Embryo Development In Vitro
Sign Up to like & getrecommendations! Published in 2024 at "Molecular Reproduction and Development"
DOI: 10.1002/mrd.70008
Abstract: The composition of the culture medium affects the viability and developmental competency of porcine embryos produced in vitro. Previous transcriptional profiling has identified areas of improvement in the formulation of these media. Xenobiotic metabolism‐related genes… read more here.
Keywords: gentamicin; development; porcine embryos; culture ... See more keywords
Use of aminoglycoside antibiotics in equine clinical practice; a questionnaire‐based study of current use
Sign Up to like & getrecommendations! Published in 2020 at "Veterinary Medicine and Science"
DOI: 10.1002/vms3.382
Abstract: Abstract Veterinary use of the aminoglycoside antibiotics is under increasing scrutiny. This questionnaire‐based study aimed to document the use of aminoglycosides with a particular focus on gentamicin. An online questionnaire was delivered to generalist equine… read more here.
Keywords: medicine; administration; aminoglycoside antibiotics; gentamicin ... See more keywords
A novel pharmacological strategy using nanoparticles with glutathione and virgin coconut oil to treat gentamicin-induced acute renal failure in rats
Sign Up to like & getrecommendations! Published in 2024 at "Naunyn-Schmiedeberg's Archives of Pharmacology"
DOI: 10.1007/s00210-024-03303-4
Abstract: In acute renal failure (ARF), the glomerular filtration rate is reduced, and nitrogenous waste products accumulate persistently, which can last anywhere from a few hours to several days. There is hope for a reversal of… read more here.
Keywords: gentamicin; renal failure; induced acute; gentamicin induced ... See more keywords
Effects of intratympanic gentamicin and intratympanic glucocorticoids in Ménière’s disease: a network meta-analysis
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Neurology"
DOI: 10.1007/s00415-020-10320-9
Abstract: Objective Intratympanic therapies, usually including glucocorticoid and gentamicin, are becoming worldwide used in clinical practice of Ménière’s disease today. However, clinical efficacy and safety of these two therapies are still in controversial. Data sources Electronic… read more here.
Keywords: gentamicin; glucocorticoids disease; intratympanic gentamicin; gentamicin glucocorticoids ... See more keywords
Quality and Clinical Outcomes Associated with a Gentamicin Use System Change for Managing Chorioamnionitis
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Medical Systems"
DOI: 10.1007/s10916-017-0856-7
Abstract: Chorioamnionitis is an intra-amniotic infection with serious maternal and neonatal complications. Clinical studies suggest antibiotic administration before delivery reduces the risk of complications compared to after delivery. Our center implemented a standardized intrapartum gentamicin computerized… read more here.
Keywords: system; gentamicin; clinical outcomes; system changes ... See more keywords
Application of topical gentamicin—a new era in the treatment of genodermatosis
Sign Up to like & getrecommendations! Published in 2021 at "World Journal of Pediatrics"
DOI: 10.1007/s12519-021-00469-2
Abstract: The clinical use of gentamicin always lies in its antimicrobial activity in the past as an aminoglycoside antibiotic. However, in the past decade, there were considerable interests in therapeutic approaches in treating hereditary diseases. Some… read more here.
Keywords: gentamicin; treatment; genodermatosis; topical gentamicin ... See more keywords
Renoprotective effect of celecoxib against gentamicin-induced nephrotoxicity through suppressing NFκB and caspase-3 signaling pathways in rats.
Sign Up to like & getrecommendations! Published in 2019 at "Chemico-biological interactions"
DOI: 10.1016/j.cbi.2019.108863
Abstract: Gentamicin-induced nephrotoxicity has been well documented, although the causing mechanisms and preventative measures need further investigation. The current study aimed to explore the potential protective impacts of celecoxib, a selective cyclooxygenase-2 (COX-2) inhibitor, on gentamicin-induced… read more here.
Keywords: protein; celecoxib; gentamicin; induced nephrotoxicity ... See more keywords
Bacteria-triggered hyaluronan/AgNPs/gentamicin nanocarrier for synergistic bacteria disinfection and wound healing application
Sign Up to like & getrecommendations! Published in 2020 at "Chemical Engineering Journal"
DOI: 10.1016/j.cej.2019.122582
Abstract: Abstract Here, we report on a bacteria-triggered hyaluronan/AgNPs/gentamicin nanocarrier (HB/Ag/g) that has highly efficient synergistic bacteria disinfection capability, and intelligent application in wound healing when used in combination with mussel-inspired chitin hydrogel. Briefly, HB/Ag/g was… read more here.
Keywords: wound healing; gentamicin; hyaluronan agnps; bacteria triggered ... See more keywords
Proof‑of‑concept study to quantify changes in intestinal loads of KPC-producing Klebsiella pneumoniae in colonized patients following selective digestive decontamination with oral gentamicin.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of global antimicrobial resistance"
DOI: 10.1016/j.jgar.2022.04.010
Abstract: OBJECTIVES To monitor quantitatively the extent of intestinal colonization by KPC-producing Klebsiella pneumoniae (KPC-Kp) in colonized patients who receive selective digestive decontamination (SDD) with oral gentamicin. METHODS We developed a real-time quantitative PCR (qPCR) method for… read more here.
Keywords: kpc producing; producing klebsiella; gentamicin; colonized patients ... See more keywords