Antibacterial Layer‐by‐Layer Films of Poly(acrylic acid)–Gentamicin Complexes with a Combined Burst and Sustainable Release of Gentamicin
Sign Up to like & getrecommendations! Published in 2019 at "Advanced Materials Interfaces"
DOI: 10.1002/admi.201901373
Abstract: The widespread nature of bacterial infections and their increasing resistance to antibiotics has led to the development of antibacterial coatings in multiple medical settings, especially on bone implants.[1] The surface of implants is susceptible to… read more here.
Keywords: release gentamicin; surgery; gentamicin; layer ... See more keywords
Hair cell uptake of gentamicin in the developing mouse utricle
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.30228
Abstract: Intratympanic injection of gentamicin has proven to be an effective therapy for intractable vestibular dysfunction. However, most studies to date have focused on the cochlea, so little is known about the distribution and uptake of… read more here.
Keywords: met channels; gentamicin; hcs; hair ... See more keywords
Use of aminoglycoside antibiotics in equine clinical practice; a questionnaire‐based study of current use
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DOI: 10.1002/vms3.382
Abstract: Abstract Veterinary use of the aminoglycoside antibiotics is under increasing scrutiny. This questionnaire‐based study aimed to document the use of aminoglycosides with a particular focus on gentamicin. An online questionnaire was delivered to generalist equine… read more here.
Keywords: medicine; administration; aminoglycoside antibiotics; gentamicin ... See more keywords
Effects of intratympanic gentamicin and intratympanic glucocorticoids in Ménière’s disease: a network meta-analysis
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Neurology"
DOI: 10.1007/s00415-020-10320-9
Abstract: Objective Intratympanic therapies, usually including glucocorticoid and gentamicin, are becoming worldwide used in clinical practice of Ménière’s disease today. However, clinical efficacy and safety of these two therapies are still in controversial. Data sources Electronic… read more here.
Keywords: gentamicin; glucocorticoids disease; intratympanic gentamicin; gentamicin glucocorticoids ... See more keywords
Quality and Clinical Outcomes Associated with a Gentamicin Use System Change for Managing Chorioamnionitis
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DOI: 10.1007/s10916-017-0856-7
Abstract: Chorioamnionitis is an intra-amniotic infection with serious maternal and neonatal complications. Clinical studies suggest antibiotic administration before delivery reduces the risk of complications compared to after delivery. Our center implemented a standardized intrapartum gentamicin computerized… read more here.
Keywords: system; gentamicin; clinical outcomes; system changes ... See more keywords
Application of topical gentamicin—a new era in the treatment of genodermatosis
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DOI: 10.1007/s12519-021-00469-2
Abstract: The clinical use of gentamicin always lies in its antimicrobial activity in the past as an aminoglycoside antibiotic. However, in the past decade, there were considerable interests in therapeutic approaches in treating hereditary diseases. Some… read more here.
Keywords: gentamicin; treatment; genodermatosis; topical gentamicin ... See more keywords
Renoprotective effect of celecoxib against gentamicin-induced nephrotoxicity through suppressing NFκB and caspase-3 signaling pathways in rats.
Sign Up to like & getrecommendations! Published in 2019 at "Chemico-biological interactions"
DOI: 10.1016/j.cbi.2019.108863
Abstract: Gentamicin-induced nephrotoxicity has been well documented, although the causing mechanisms and preventative measures need further investigation. The current study aimed to explore the potential protective impacts of celecoxib, a selective cyclooxygenase-2 (COX-2) inhibitor, on gentamicin-induced… read more here.
Keywords: protein; celecoxib; gentamicin; induced nephrotoxicity ... See more keywords
Bacteria-triggered hyaluronan/AgNPs/gentamicin nanocarrier for synergistic bacteria disinfection and wound healing application
Sign Up to like & getrecommendations! Published in 2020 at "Chemical Engineering Journal"
DOI: 10.1016/j.cej.2019.122582
Abstract: Abstract Here, we report on a bacteria-triggered hyaluronan/AgNPs/gentamicin nanocarrier (HB/Ag/g) that has highly efficient synergistic bacteria disinfection capability, and intelligent application in wound healing when used in combination with mussel-inspired chitin hydrogel. Briefly, HB/Ag/g was… read more here.
Keywords: wound healing; gentamicin; hyaluronan agnps; bacteria triggered ... See more keywords
Proof‑of‑concept study to quantify changes in intestinal loads of KPC-producing Klebsiella pneumoniae in colonized patients following selective digestive decontamination with oral gentamicin.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of global antimicrobial resistance"
DOI: 10.1016/j.jgar.2022.04.010
Abstract: OBJECTIVES To monitor quantitatively the extent of intestinal colonization by KPC-producing Klebsiella pneumoniae (KPC-Kp) in colonized patients who receive selective digestive decontamination (SDD) with oral gentamicin. METHODS We developed a real-time quantitative PCR (qPCR) method for… read more here.
Keywords: kpc producing; producing klebsiella; gentamicin; colonized patients ... See more keywords
Ferulic acid promotes survival and differentiation of neural stem cells to prevent gentamicin‐induced neuronal hearing loss
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DOI: 10.1016/j.yexcr.2017.09.015
Abstract: Abstract Neural stem cells (NSCs) have exhibited promising potential in therapies against neuronal hearing loss. Ferulic acid (FA) has been widely reported to enhance neurogenic differentiation of different stem cells. We investigated the role of… read more here.
Keywords: hearing loss; differentiation; gentamicin; neuronal hearing ... See more keywords
The Effect of Operating Strategies on the Anaerobic Digestion of Gentamicin Mycelial Residues: Insights into the Enhancement of Methane Production and Attenuation of Gentamicin Resistance.
Sign Up to like & getrecommendations! Published in 2022 at "Environmental science & technology"
DOI: 10.1021/acs.est.2c00481
Abstract: Anaerobic digestion (AD) has been widely employed for converting various biowastes into renewable energy. However, AD of gentamicin mycelial residues (GMRs, a byproduct of gentamicin production) is limited by ammonia inhibition and antimicrobial resistance risk.… read more here.
Keywords: anaerobic digestion; production; resistance; gentamicin mycelial ... See more keywords