A review on gentisic acid as a plant derived phenolic acid and metabolite of aspirin: Comprehensive pharmacology, toxicology, and some pharmaceutical aspects
Sign Up to like & getrecommendations! Published in 2019 at "Phytotherapy Research"
DOI: 10.1002/ptr.6573
Abstract: Beneficial therapeutic effects of phenolic acids have been proven in various research projects including in vivo and in vitro studies. Gentisic acid (GA) is a phenolic acid that has been associated with useful effects on… read more here.
Keywords: metabolite aspirin; pharmacology; gentisic acid; toxicology ... See more keywords
From epidemiology to treatment: Aspirin's prevention of brain and breast-cancer and cardioprotection may associate with its metabolite gentisic acid.
Sign Up to like & getrecommendations! Published in 2018 at "Chemico-biological interactions"
DOI: 10.1016/j.cbi.2018.05.016
Abstract: BACKGROUND Epidemiological studies indicate that aspirin consumption reduces the risk of tumors, which is especially relevant for colonic adenoma and carcinoma. Similar observations were made for glial brain tumors and breast cancers, yet the results… read more here.
Keywords: growth; epidemiology; brain; gentisic acid ... See more keywords
Different inhibition mechanisms of gentisic acid and cyaniding-3-O-glucoside on polyphenoloxidase.
Sign Up to like & getrecommendations! Published in 2017 at "Food chemistry"
DOI: 10.1016/j.foodchem.2017.05.010
Abstract: Gentisic acid and cyanidin-3-O-glucoside are important bioactive polyphenols which are widely distributed in many fruits and cereals. In this work, kinetic study, spectral analysis and computational simulation were used to compare the inhibitory effects and… read more here.
Keywords: cyanidin glucoside; gentisic acid; acid cyanidin;
Design, synthesis and characterization of lysozyme-gentisic acid dual-functional conjugates with antibacterial/antioxidant activities.
Sign Up to like & getrecommendations! Published in 2021 at "Food chemistry"
DOI: 10.1016/j.foodchem.2021.131032
Abstract: Both microbiological and chemical food spoilages remain to be the major challenges in the food industry's efforts to combat food waste and loss because of the lack of high efficacy food preservatives. In this study,… read more here.
Keywords: lysozyme; dual functional; functional conjugates; gentisic acid ... See more keywords
Improving Antioxidant Activity of β-Lactoglobulin by Nature-inspired Conjugation with Gentisic Acid.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of agricultural and food chemistry"
DOI: 10.1021/acs.jafc.9b05304
Abstract: Dietary phenolic compounds display strong antioxidant capabilities but face limited practical applications due to their poor biocompatibility (high immune-resistance). Some food proteins possess mild antioxidant capabilities but are often not sufficient to maintain ROS balance.… read more here.
Keywords: antioxidant activity; nature inspired; spectroscopy; conjugation ... See more keywords
Novel absorbance peak of gentisic acid following the oxidation reaction
Sign Up to like & getrecommendations! Published in 2020 at "PLoS ONE"
DOI: 10.1371/journal.pone.0232263
Abstract: Gentisic acid (GA), a metabolite of acetylsalicylic acid (ASA), and homogentisic acid (HGA), which is excreted at high levels in alkaptonuria, are divalent phenolic acids with very similar structures. Urine containing HGA is dark brown… read more here.
Keywords: oxidation reaction; hga; oxidation; acid ... See more keywords