0288 Wakefulness by Optostimulation of Basal Forebrain vGluT2+ Neurons Trigger Different Patterns of Brain Activity and Recovery Sleep from Gentle Handling
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DOI: 10.1093/sleep/zsaf090.0288
Abstract: Prolonged wakefulness induces a homeostatic sleep response (HSR) with increases in non-REM sleep time and delta power. The quality of wakefulness impacts the magnitude and form of the HSR but little is known about the… read more here.
Keywords: brain; gentle handling; wakefulness; basal forebrain ... See more keywords
Handling and novel object recognition modulate fear response and endocannabinoid signaling in nucleus basalis magnocellularis
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DOI: 10.1111/ejn.15642
Abstract: Storage of aversive memories is of utmost importance for survival, allowing animals to avoid upcoming similar stimuli. However, without reinforcement, the learned avoidance response gradually decreases over time. Although the molecular mechanisms controlling this extinction… read more here.
Keywords: response; gentle handling; nucleus basalis; novel object ... See more keywords
The Effect of Gentle Handling on Depressive-Like Behavior in Adult Male Mice: Considerations for Human and Rodent Interactions in the Laboratory
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DOI: 10.1155/2018/2976014
Abstract: Environmental factors play a significant role in well-being of laboratory animals. Regulations and guidelines recommend, if not require, that stressors such as bright lighting, smells, and noises are eliminated or reduced to maximize animal well-being.… read more here.
Keywords: adult; gentle handling; like behavior; male mice ... See more keywords