The S2 Pocket Governs the Genus‐Specific Substrate Selectivity of Coronavirus 3C‐Like Protease
Sign Up to like & getrecommendations! Published in 2024 at "Advanced Science"
DOI: 10.1002/advs.202407766
Abstract: Coronavirus 3C‐like protease (CoV 3CLpro) is essential for viral replication, providing an attractive target for monitoring the evolution of CoV and developing anti‐CoV drugs. Here, the substrate‐binding modes of 3CLpros from four CoV genera are… read more here.
Keywords: like protease; coronavirus like; pocket; genus specific ... See more keywords
Quantifying dominant bacterial genera detected in metagenomic data from fish eggs and larvae using genus‐specific primers
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DOI: 10.1002/mbo3.1274
Abstract: The goal of this study was to design genus‐specific primers for rapid evaluation of the most abundant bacterial genera identified using amplicon‐based sequencing of the 16S rRNA gene in fish‐related samples and surrounding water. Efficient… read more here.
Keywords: bacterial genera; specific primers; 16s rrna; genus specific ... See more keywords
Genus-specific pattern of intrinsically disordered central regions in the nucleocapsid protein of coronaviruses
Sign Up to like & getrecommendations! Published in 2020 at "Computational and Structural Biotechnology Journal"
DOI: 10.1016/j.csbj.2020.07.005
Abstract: Abstract The nucleocapsid (N) protein is conserved in all four genera of the coronaviruses, namely alpha, beta, gamma, and delta, and is essential for genome functionality. Bioinformatic analysis of coronaviral N sequences revealed two intrinsically… read more here.
Keywords: pattern intrinsically; disordered central; specific pattern; genus specific ... See more keywords
Enrichment of Viral Nucleic Acids by Solution Hybrid Selection with Genus Specific Oligonucleotides
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DOI: 10.1038/s41598-017-10342-w
Abstract: Despite recent advances, our knowledge of potential and rare human pathogens is far from exhaustive. Current molecular diagnostic tools mainly rely on the specific amplification of marker sequences and may overlook infections caused by unknown… read more here.
Keywords: enrichment viral; nucleic acids; genus; genus specific ... See more keywords
Comparative genomics reveals a core gene toolbox for lifestyle transitions in Hypocreales fungi
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DOI: 10.1111/1462-2920.15554
Abstract: Summary Fungi have evolved diverse lifestyles and adopted pivotal new roles in both natural ecosystems and human environments. However, the molecular mechanisms underlying their adaptation to new lifestyles are obscure. Here, we hypothesize that genes… read more here.
Keywords: comparative genomics; lifestyle transitions; genus specific; specific genes ... See more keywords
DNA barcoding insufficiently identifies European wild bees (Hymenoptera, Anthophila) due to undefined species diversity, genus‐specific barcoding gaps and database errors
Sign Up to like & getrecommendations! Published in 2024 at "Molecular Ecology Resources"
DOI: 10.1111/1755-0998.13953
Abstract: Recent declines in insect abundances, especially populations of wild pollinators, pose a threat to many natural and agricultural ecosystems. Traditional species monitoring relies on morphological character identification and is inadequate for efficient and standardized surveys.… read more here.
Keywords: specific barcoding; wild bees; european wild; identification ... See more keywords
Evaluation of the Bacterial Diversity in the Human Tongue Coating Based on Genus-Specific Primers for 16S rRNA Sequencing
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DOI: 10.1155/2017/8184160
Abstract: The characteristics of tongue coating are very important symbols for disease diagnosis in traditional Chinese medicine (TCM) theory. As a habitat of oral microbiota, bacteria on the tongue dorsum have been proved to be the… read more here.
Keywords: tongue coating; 16s rrna; based genus; genus specific ... See more keywords
Development of a genus-specific next generation sequencing approach for sensitive and quantitative determination of the Legionella microbiome in freshwater systems
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DOI: 10.1186/s12866-017-0987-5
Abstract: BackgroundNext Generation Sequencing (NGS) has revolutionized the analysis of natural and man-made microbial communities by using universal primers for bacteria in a PCR based approach targeting the 16S rRNA gene. In our study we narrowed… read more here.
Keywords: ngs approach; genus specific; approach; legionella ... See more keywords
Genus-Specific Molecular Markers for In Vitro Detection of Corinectria Forest Pathogens
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DOI: 10.3390/f16040697
Abstract: Canker disease caused by Corinectria constricta has resulted in significant losses of Pinus radiata for the Chilean forestry industry in recent years. Accurate and prompt detection and identification of the pathogen is essential in this… read more here.
Keywords: detection; molecular markers; markers vitro; corinectria ... See more keywords