A geographically matched control population efficiently limits the number of candidate disease-causing variants in an unbiased whole-genome analysis
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DOI: 10.1371/journal.pone.0213350
Abstract: Whole-genome sequencing is a promising approach for human autosomal dominant disease studies. However, the vast number of genetic variants observed by this method constitutes a challenge when trying to identify the causal variants. This is… read more here.
Keywords: control population; number; disease; geographically matched ... See more keywords