Vanadium-Catalyzed Synthesis of Geometrically Defined Acyclic Tri- and Tetrasubstituted Olefins from Propargyl Alcohols
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DOI: 10.1021/acscatal.8b04567
Abstract: A highly selective formation of geometrically defined acyclic tri- and tetrasubstituted alkenes from inexpensive and readily available propargyl alcohols is described. Through vanadium oxo catalysis, tri- and tetrasubstituted α-chloro-, bromo-, and iodo-enone olefins can be… read more here.
Keywords: geometry; defined acyclic; tri tetrasubstituted; acyclic tri ... See more keywords
Isomerization of N-Allyl Amides To Form Geometrically Defined Di-, Tri-, and Tetrasubstituted Enamides.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.7b00564
Abstract: Enamides represent bioactive pharmacophores in various natural products, and have become increasingly common reagents for asymmetric incorporation of nitrogen functionality. Yet the synthesis of the requisite geometrically defined enamides remains problematic, especially for highly substituted… read more here.
Keywords: amides form; allyl amides; isomerization; tri tetrasubstituted ... See more keywords