Articles with "gep nec" as a keyword



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Spartalizumab in metastatic, well/poorly-differentiated neuroendocrine neoplasms.

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Published in 2021 at "Endocrine-related cancer"

DOI: 10.1530/erc-20-0382

Abstract: Spartalizumab, a humanized anti-programmed death protein 1 (PD-1) monoclonal antibody, was evaluated in patients with well-differentiated metastatic grade 1/2 neuroendocrine tumors (NET) and poorly-differentiated gastroenteropancreatic neuroendocrine carcinomas (GEP-NEC). In this phase II, multicenter, single-arm study,… read more here.

Keywords: gep nec; net group; nec group; spartalizumab metastatic ... See more keywords
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First-line treatment of camrelizumab combined with chemotherapy in advanced gastroenteropancreatic neuroendocrine carcinoma: Study protocol for a prospective, multicenter, phase II study

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Published in 2022 at "Frontiers in Oncology"

DOI: 10.3389/fonc.2022.958905

Abstract: Background Gastroenteropancreatic neuroendocrine carcinoma (GEP-NEC) is a group of rare but highly aggressive malignancies. The standard chemotherapy regimens composed of etoposide and cisplatin/carboplatin (EP/EC) are of limited efficacy. This prospective, multicenter, phase II study is… read more here.

Keywords: first line; gep nec; chemotherapy; camrelizumab ... See more keywords