Radical intended surgery for highly selected stage IV neuroendocrine neoplasms G3.
Sign Up to like & getrecommendations! Published in 2020 at "American journal of surgery"
DOI: 10.1016/j.amjsurg.2020.03.009
Abstract: BACKGROUND Stage IV gastro-entero-pancreatic neuroendocrine neoplasms (GEP-NENs) G3 are the NENs with the worst prognosis. According to ENETS guidelines, platinum-based chemotherapy is the standard treatment for this population. Surgery is only considered in highly selected… read more here.
Keywords: intended surgery; gep nens; surgery; neuroendocrine neoplasms ... See more keywords
Efficacy and Toxicity of 5-Fluorouracil–Oxaliplatin in Gastroenteropancreatic Neuroendocrine Neoplasms
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DOI: 10.1097/mpa.0000000000001593
Abstract: Supplemental digital content is available in the text. Objectives The objective of this study was to investigate the efficacy and tolerability of 5-fluorouracil–oxaliplatin (FOLFOX) in advanced gastroenteropancreatic neuroendocrine neoplasms (GEP-NENs). Methods Retrospective analysis of consecutive… read more here.
Keywords: fluorouracil oxaliplatin; gep nens; gastroenteropancreatic neuroendocrine; neuroendocrine neoplasms ... See more keywords
Role of immunotherapy in gastro‐enteropancreatic neuroendocrine neoplasms (gep‐nens): Current advances and future directions
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DOI: 10.1111/jne.12943
Abstract: Neuroendocrine neoplasms (NENs) are heterogeneous tumours originating from neuroendocrine cells (Pearse & Polak, Gut, 1971, 12,783). They were once considered as rare tumours, although their annual incidence has increased significantly and now exceeds seven cases… read more here.
Keywords: gep nens; gastro enteropancreatic; neuroendocrine neoplasms; oncology ... See more keywords
Comprehensive Genomic Profiling of Gastroenteropancreatic Neuroendocrine Neoplasms (GEP-NENs)
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DOI: 10.1158/1078-0432.ccr-20-1804
Abstract: Purpose: GEP-NENs are rare malignancies with increasing incidence. Their molecular characteristics are still undefined. We explored the underlying biology of GEP-NENs and the differences between gastrointestinal (GI) and pancreatic (PNEN), high-grade (HG), and low-grade (LG)… read more here.
Keywords: genomic profiling; gep nens; biology; profiling gastroenteropancreatic ... See more keywords
Update on Epidemiology, Diagnosis, and Biomarkers in Gastroenteropancreatic Neuroendocrine Neoplasms
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DOI: 10.3390/cancers14051119
Abstract: Simple Summary Neuroendocrine neoplasms are divided into two groups: well-differentiated neuroendocrine tumors and poorly differentiated neuroendocrine carcinomas. The progress in diagnostic methods, including pathology optimization and imaging, might be one of the reasons for the… read more here.
Keywords: epidemiology; gastroenteropancreatic neuroendocrine; neuroendocrine neoplasms; epidemiology diagnosis ... See more keywords
Advances in the Diagnosis and Therapeutic Management of Gastroenteropancreatic Neuroendocrine Neoplasms (GEP-NENs)
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DOI: 10.3390/cancers14082028
Abstract: Simple Summary Gastroenteropancreatic neuroendocrine neoplasms (GEP-NENs) are a group of tumors with different clinical manifestations, various localizations in the human body, and a particularly wide range of histological types, grades and severities. Their diagnosis and… read more here.
Keywords: gep nens; management; gastroenteropancreatic neuroendocrine; treatment ... See more keywords
Role of Combined 68Ga DOTA-Peptides and 18F FDG PET/CT in the Evaluation of Gastroenteropancreatic Neuroendocrine Neoplasms
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DOI: 10.3390/diagnostics12020280
Abstract: This review article summarizes the role of combined 68Ga DOTA-peptides and 18F-fluorodeoxyglucose (FDG) positron emission tomography/computed tomography (PET/CT) in the evaluation of gastroenteropancreatic neuroendocrine neoplasms (GEP-NENs). Patients with GEP-NENs can initially present themselves to a… read more here.
Keywords: peptides 18f; dota peptides; gep nens; 68ga dota ... See more keywords
New insights in diagnosis and treatment of gastroenteropancreatic neuroendocrine neoplasms
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DOI: 10.3748/wjg.v28.i17.1751
Abstract: Gastroenteropancreatic neuroendocrine neoplasms (GEP-NENs) are rare epithelial neoplasms derived from pluripotent endocrine cells along the gastrointestinal tract and pancreas. GEP-NENs are classified into well-differentiated neuroendocrine tumors and poorly differentiated neuroendocrine carcinomas. Despite overlapping morphological features,… read more here.
Keywords: diagnosis; gep nens; neuroendocrine neoplasms; treatment ... See more keywords