Potential role of two cytochrome P450s obtained from Lithospermum erythrorhizon in catalyzing the oxidation of geranylhydroquinone during Shikonin biosynthesis.
Sign Up to like & getrecommendations! Published in 2020 at "Phytochemistry"
DOI: 10.1016/j.phytochem.2020.112375
Abstract: Shikonin is a natural naphthoquinone derivative that specifically occurs in boraginaceous plants, and the major active ingredient of the medicinal plant Lithospermum erythrorhizon. Previously, a cytochrome P450 oxygenase (CYP) CYP76B74 catalyzing 3″-hydroxylation of geranylhydroquinone (GHQ)… read more here.
Keywords: catalyzing oxidation; oxidation; ghq; geranylhydroquinone ... See more keywords
CYP76B74 Catalyzes the 3′′-Hydroxylation of Geranylhydroquinone in Shikonin Biosynthesis1
Sign Up to like & getrecommendations! Published in 2018 at "Plant Physiology"
DOI: 10.1104/pp.18.01056
Abstract: CYP76B74 encodes geranylhydroquinone 3′′-hydroxylase involved in the shikonin biosynthetic pathway and is necessary for the accumulation of shikonin derivatives in Arnebia euchroma. Shikonin and its derivatives are the most abundant naphthoquinone pigments formed in species… read more here.
Keywords: hydroxylase; hydroxylation; cyp76b74 catalyzes; shikonin ... See more keywords