Computational modeling offers new insight into Drosophila germ granule development.
Sign Up to like & getrecommendations! Published in 2022 at "Biophysical journal"
DOI: 10.1016/j.bpj.2022.03.014
Abstract: The packaging of specific mRNAs into ribonucleoprotein granules called germ granules is required for germline proliferation and maintenance. During Drosophila germ granule development, mRNAs such as nanos (nos) and polar granule component (pgc) localize to… read more here.
Keywords: granule development; germ granule; drosophila germ; granule ... See more keywords
Nucleoporins shape germ granule architecture and balance small RNA silencing pathways
Sign Up to like & getrecommendations! Published in 2025 at "Nature Communications"
DOI: 10.1038/s41467-025-59526-3
Abstract: Animals use small RNA pathways, such as PIWI-interacting RNA (piRNA) and small interfering RNA (siRNA), to silence harmful genetic elements. In Caenorhabditis elegans, piRNA pathway components are organized into sub-compartments within germ granules near nuclear… read more here.
Keywords: germ granule; small rna; germ granules; rna silencing ... See more keywords