Posthemorrhagic hydrocephalus development after germinal matrix hemorrhage: Established mechanisms and proposed pathways
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Neuroscience Research"
DOI: 10.1002/jnr.24394
Abstract: In addition to being the leading cause of morbidity and mortality in premature infants, germinal matrix hemorrhage (GMH) is also the leading cause of acquired infantile hydrocephalus. The pathophysiology of posthemorrhagic hydrocephalus (PHH) development after… read more here.
Keywords: etiology; posthemorrhagic hydrocephalus; matrix hemorrhage; germinal matrix ... See more keywords
Research Advances of Germinal Matrix Hemorrhage: An Update Review
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DOI: 10.1007/s10571-018-0630-5
Abstract: Germinal matrix hemorrhage (GMH) refers to bleeding that derives from the subependymal (or periventricular) germinal region of the premature brain. GMH can induce severe and irreversible damage attributing to the vulnerable structure of germinal matrix… read more here.
Keywords: advances germinal; hemorrhage update; research advances; matrix hemorrhage ... See more keywords
A Brain-Region-Specific Neural Pathway Regulating Germinal Matrix Angiogenesis.
Sign Up to like & getrecommendations! Published in 2017 at "Developmental cell"
DOI: 10.1016/j.devcel.2017.04.014
Abstract: Intimate communication between neural and vascular cells is critical for normal brain development and function. Germinal matrix (GM), a key primordium for the brain reward circuitry, is unique among brain regions for its distinct pace… read more here.
Keywords: specific neural; region specific; brain; brain region ... See more keywords
Serelaxin activates eNOS, suppresses inflammation, attenuates developmental delay and improves cognitive functions of neonatal rats after germinal matrix hemorrhage
Sign Up to like & getrecommendations! Published in 2020 at "Scientific Reports"
DOI: 10.1038/s41598-020-65144-4
Abstract: Germinal matrix hemorrhage (GMH) is a detrimental form of neonatal CNS injury. Following GMH-mediated eNOS inhibition, inflammation arises, contributing to GMH-induced brain injury. We investigated the beneficial effects of Serelaxin, a clinical tested recombinant Relaxin-2… read more here.
Keywords: serelaxin; inflammation; gmh induced; matrix hemorrhage ... See more keywords
NT-4 attenuates neuroinflammation via TrkB/PI3K/FoxO1 pathway after germinal matrix hemorrhage in neonatal rats
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Neuroinflammation"
DOI: 10.1186/s12974-020-01835-z
Abstract: Background Neuroinflammation plays an important role in pathogenesis of germinal matrix hemorrhage (GMH). Neurotrophin-4 (NT-4) is a member of the neurotrophin family and interacts with the tropomyosin receptor kinase B (TrkB). NT-4 has been shown… read more here.
Keywords: pi3k; trkb pi3k; expression; matrix hemorrhage ... See more keywords
Reducing Germinal Matrix-Intraventricular Hemorrhage: Perinatal and Delivery Room Factors.
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DOI: 10.1542/neo.20-8-e452
Abstract: Germinal matrix hemorrhage-intraventricular hemorrhage (IVH) is the most common form of brain injury in preterm infants. Although severe IVH has declined over the years, it still affects approximately 6% of infants born before 32 weeks… read more here.
Keywords: hemorrhage; germinal matrix; ivh; delivery room ... See more keywords
Comparison of Papile versus Laterality-Based Al-Abdi System to Predict Neurodevelopmental Impairment in Extreme Preterm Infants after Severe Germinal Matrix Hemorrhage–Intraventricular Hemorrhage: A Retrospective Comparative Observational Study
Sign Up to like & getrecommendations! Published in 2022 at "American Journal of Neuroradiology"
DOI: 10.3174/ajnr.a7434
Abstract: The Al-Abdi system is comparable with the Papile system for predicting neurodevelopmental impairment for extremely preterm infants with severe germinal matrix hemorrhage-intraventricular hemorrhage, with higher Al-Abdi scores being more specific. BACKGROUND AND PURPOSE: The traditional… read more here.
Keywords: hemorrhage intraventricular; severe germinal; hemorrhage; germinal matrix ... See more keywords