Articles with "germline derived" as a keyword



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Redesigning an antibody H3 loop by virtual screening of a small library of human germline-derived sequences

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Published in 2021 at "Scientific Reports"

DOI: 10.1038/s41598-021-00669-w

Abstract: The design of superior biologic therapeutics, including antibodies and engineered proteins, involves optimizing their specific ability to bind to disease-related molecular targets. Previously, we developed and applied the Assisted Design of Antibody and Protein Therapeutics… read more here.

Keywords: antibody; derived sequences; human germline; redesigning antibody ... See more keywords