Articles with "germline editing" as a keyword



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Human germline editing: Insights to future clinical treatment of diseases

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Published in 2018 at "Protein & Cell"

DOI: 10.1007/s13238-018-0594-8

Abstract: 1 Key Laboratory for Major Obstetric Diseases of Guangdong Province, Center of Reproductive Medicine, The Third Affiliated Hospital of Guangzhou Medical University, Guangzhou 510150, China 2 Disease Modeling and Therapeutics Laboratory, A*STAR Institute of Molecular… read more here.

Keywords: insights future; medicine; editing insights; future clinical ... See more keywords
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Academies’ action plan for germline editing

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Published in 2019 at "Nature"

DOI: 10.1038/d41586-019-00813-7

Abstract: An international commission from the US National Academy of Sciences, the US National Academy of Medicine and the UK Royal Society. read more here.

Keywords: medicine; plan germline; academies action; germline editing ... See more keywords
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What now for human genome editing?

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Published in 2018 at "Science"

DOI: 10.1126/science.362.6419.1090

Abstract: In the wake of He Jiankui9s shocking announcement that his lab created the first germline-edited babies, the scientific community has done great soul searching about how this happened—and how they might prevent others from using… read more here.

Keywords: germline editing; human genome; genome editing;
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Human germline editing in the era of CRISPR-Cas: risk and uncertainty, inter-generational responsibility, therapeutic legitimacy

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Published in 2020 at "BMC Medical Ethics"

DOI: 10.1186/s12910-020-00487-1

Abstract: Background Clustered Regularly Interspaced Short Palindromic Repeats-associated (CRISPR-Cas) technology may allow for efficient and highly targeted gene editing in single-cell embryos. This possibility brings human germline editing into the focus of ethical and legal debates… read more here.

Keywords: germline; crispr cas; human germline; germline editing ... See more keywords
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Who Goes First? Deaf People and CRISPR Germline Editing.

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Published in 2020 at "Perspectives in biology and medicine"

DOI: 10.1353/pbm.2020.0004

Abstract: The development of CRISPR technology has catapulted the issue of germline editing to the forefront of a debate between the goals of medical advancement and promotion of human diversity. The US National Academy of Sciences… read more here.

Keywords: medicine; goes first; first deaf; people crispr ... See more keywords