Articles with "germline egfr" as a keyword



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Case report: Neuroendocrine breast carcinoma with a germline EGFR T790M mutation

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Published in 2023 at "Frontiers in Oncology"

DOI: 10.3389/fonc.2023.1176868

Abstract: Background The epidermal growth factor receptor (EGFR) p.Thr790Met (T790M) mutation was discovered as a resistance mechanism in patients with lung cancer treated with first- and second-generation tyrosine kinase inhibitors. Further studies revealed the EGFR T790M… read more here.

Keywords: t790m mutation; breast; germline egfr; mutation ... See more keywords
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Germline EGFR mutations in lung cancer (Review)

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Published in 2023 at "Oncology Letters"

DOI: 10.3892/ol.2023.13868

Abstract: Lung cancer is the leading cause of cancer-related death and familial lung cancer is a potential contributing factor. Epidermal growth factor receptor (EGFR) mutations are important events in carcinogenesis. The present study summarized the common… read more here.

Keywords: lung cancer; mutations lung; egfr mutations; germline egfr ... See more keywords