Germline gain‐of‐function MMP11 variant results in an aggressive form of colorectal cancer
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DOI: 10.1002/ijc.34289
Abstract: Matrix metalloproteinase‐11 (MMP11) is an enzyme with proteolytic activity against matrix and nonmatrix proteins. Although most MMPs are secreted as inactive proenzymes and are later activated extracellularly, MMP11 is activated intracellularly by furin within the… read more here.
Keywords: germline gain; cancer germline; mmp11; colorectal cancer ... See more keywords