Cellular and metabolic characteristics of pre-leukemic hematopoietic progenitors with GATA2 haploinsuficiency.
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DOI: 10.3324/haematol.2022.279437
Abstract: Mono-Allelic germline disruptions of the transcription factor GATA2 result in a propensity for developing myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML) affecting more than 85% of carriers. How a partial loss of GATA2 functionality… read more here.
Keywords: cellular metabolic; metabolic characteristics; gata2; pre leukemic ... See more keywords