henn-1/HEN1 Promotes Germline Immortality in Caenorhabditis elegans
Sign Up to like & getrecommendations! Published in 2019 at "Cell reports"
DOI: 10.1016/j.celrep.2019.10.114
Abstract: SUMMARY The germline contains an immortal cell lineage that ensures the faithful transmission of genetic and, in some instances, epigenetic information from one generation to the next. Here, we show that in Caenorhabditis elegans, the… read more here.
Keywords: henn hen1; caenorhabditis elegans; germline immortality; hen1 promotes ... See more keywords
Germline immortality relies on TRIM32-mediated turnover of a maternal mRNA activator in C. elegans
Sign Up to like & getrecommendations! Published in 2022 at "Science Advances"
DOI: 10.1126/sciadv.abn0897
Abstract: How the germ line achieves a clean transition from maternal to zygotic gene expression control is a fundamental problem in sexually reproducing organisms. Whereas several mechanisms terminate the maternal program in the soma, this combined… read more here.
Keywords: germline immortality; immortality relies; mediated turnover; relies trim32 ... See more keywords