Expansion Microscopy‐based imaging for visualization of mitochondria in Drosophila ovarian germline stem cells
Sign Up to like & getrecommendations! Published in 2022 at "FEBS Open Bio"
DOI: 10.1002/2211-5463.13506
Abstract: Recent studies have shown that mitochondrial morphology can modulate organelle function and greatly affect stem cell behavior, thus affecting tissue homeostasis. As such, we previously showed that the accumulation of fragmented mitochondria in aged Drosophila… read more here.
Keywords: drosophila ovarian; microscopy; ovarian germline; germline stem ... See more keywords
Engineering Female Germline Stem Cells with Exocytotic Polymer Dots.
Sign Up to like & getrecommendations! Published in 2023 at "Advanced materials"
DOI: 10.1002/adma.202210458
Abstract: Germline stem cells (GSCs) are the only cell population capable of passing genetic information to offspring, making them attractive targets in reproductive biology and fertility research. However, it is generally more difficult to introduce exogenous… read more here.
Keywords: engineering female; polymer dots; germline stem; female germline ... See more keywords
Canonical and non‐canonical functions of STAT in germline stem cell maintenance
Sign Up to like & getrecommendations! Published in 2023 at "Developmental Dynamics"
DOI: 10.1002/dvdy.576
Abstract: Maintenance of the Drosophila male germline stem cells (GSCs) requires activation of the Janus kinase/signal transducer and activators of transcription (JAK/STAT) pathway by niche signals. The precise role of JAK/STAT signaling in GSC maintenance, however,… read more here.
Keywords: canonical functions; canonical non; maintenance; non canonical ... See more keywords
H19 regulates the proliferation of bovine male germline stem cells via IGF‐1 signaling pathway
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.26920
Abstract: Self‐renewal and differentiation of male germline stem cells (mGSCs) provide the basic function for continual spermatogenesis. Studies of in vitro culture of germline stem cells are important and meaningful for basic biological research and practical… read more here.
Keywords: igf signaling; germline stem; signaling pathway; igf ... See more keywords
Mitochondrial Redox Sensor for Drosophila Female Germline Stem Cells.
Sign Up to like & getrecommendations! Published in 2019 at "Methods in molecular biology"
DOI: 10.1007/7651_2018_167
Abstract: Mitochondrial reactive oxygen species (mROS), a major source of ROS within cells, functions as an important signaling molecule and has the ability to damage cellular macromolecules including DNA and proteins. Monitoring mROS levels is therefore… read more here.
Keywords: redox sensor; germline stem; stem cells;
Tracking Germline Stem Cell Dynamics In Vivo in C. elegans Using Photoconversion.
Sign Up to like & getrecommendations! Published in 2019 at "Methods in molecular biology"
DOI: 10.1007/7651_2019_225
Abstract: The maintenance of many adult tissues depends on stem cell systems, which must balance proliferation and differentiation. To understand the properties of adult stem cell systems, one powerful tool is visualization of the cell dynamics… read more here.
Keywords: cell dynamics; germline stem; stem cell; photoconversion ... See more keywords
Molecular control of the female germline stem cell niche size in Drosophila
Sign Up to like & getrecommendations! Published in 2019 at "Cellular and Molecular Life Sciences"
DOI: 10.1007/s00018-019-03223-0
Abstract: Adult stem cells have a unique capacity to renew themselves and generate differentiated cells that are needed in the body. These cells are recruited and maintained by the surrounding microenvironment, known as the stem cell… read more here.
Keywords: cell niche; germline stem; stem cell; niche ... See more keywords
Aubergine Controls Germline Stem Cell Self-Renewal and Progeny Differentiation via Distinct Mechanisms.
Sign Up to like & getrecommendations! Published in 2017 at "Developmental cell"
DOI: 10.1016/j.devcel.2017.03.023
Abstract: Piwi family protein Aubergine (Aub) maintains genome integrity in late germ cells of the Drosophila ovary through Piwi-associated RNA-mediated repression of transposon activities. Although it is highly expressed in germline stem cells (GSCs) and early… read more here.
Keywords: germline stem; self renewal; differentiation; cell ... See more keywords
miR-9a modulates maintenance and ageing of Drosophila germline stem cells by limiting N-cadherin expression
Sign Up to like & getrecommendations! Published in 2017 at "Nature Communications"
DOI: 10.1038/s41467-017-00485-9
Abstract: Ageing is characterized by a decline in stem cell functionality leading to dampened tissue regeneration. While the expression of microRNAs across multiple species is markedly altered with age, the mechanism by which they govern stem… read more here.
Keywords: germline stem; mir; expression; ageing drosophila ... See more keywords
LIN‐28 balances longevity and germline stem cell number in Caenorhabditis elegans through let‐7/AKT/DAF‐16 axis
Sign Up to like & getrecommendations! Published in 2017 at "Aging Cell"
DOI: 10.1111/acel.12539
Abstract: The RNA‐binding protein LIN‐28 was first found to control developmental timing in Caenorhabditis elegans. Later, it was found to play important roles in pluripotency, metabolism, and cancer in mammals. Here we report that a low… read more here.
Keywords: stem cell; germline stem; cell number; lin ... See more keywords
Role of the Hedgehog Signaling Pathway in Regulating the Behavior of Germline Stem Cells
Sign Up to like & getrecommendations! Published in 2017 at "Stem Cells International"
DOI: 10.1155/2017/5714608
Abstract: Germline stem cells (GSCs) are adult stem cells that are responsible for the production of gametes and include spermatogonial stem cells (SSCs) and ovarian germline stem cells (OGSCs). GSCs are located in a specialized microenvironment… read more here.
Keywords: hedgehog signaling; germline stem; signaling pathway; role ... See more keywords