Gestational exposure to nicotine and/or benzo[a]pyrene causes long-lasting neurobehavioral consequences.
Sign Up to like & getrecommendations! Published in 2019 at "Birth defects research"
DOI: 10.1002/bdr2.1568
Abstract: Tobacco smoke is a complex mixture that includes thousands of compounds. Previously, we have found that gestational exposure to the complex mixture of tobacco smoke extract caused long-term neurobehavioral impairments. In this study, we examined… read more here.
Keywords: gestational exposure; nicotine benzo; benzo pyrene; sex ... See more keywords
Gestational exposure to continuous light impairs the development of the female reproductive system in adult Wistar rat offspring
Sign Up to like & getrecommendations! Published in 2023 at "Birth Defects Research"
DOI: 10.1002/bdr2.2161
Abstract: It has been suggested that maternal exposure to constant light during the gestational period could be considered as a chronic stressor, impairing offspring development by interfering in neuroendocrine and behavior responses. read more here.
Keywords: light impairs; development; exposure continuous; gestational exposure ... See more keywords
Gestational exposure to acrylamide inhibits mouse placental development in vivo.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of hazardous materials"
DOI: 10.1016/j.jhazmat.2018.12.061
Abstract: Acrylamide, a carcinogen and neurotoxic substance, recently has been discovered in various heat-treated carbohydrate-rich foods. The aim of this study was to investigate the effects of acrylamide exposure on placental development. Pregnant mice received acrylamide… read more here.
Keywords: placental development; exposure acrylamide; gestational exposure; exposure ... See more keywords
Gestational exposure to paracetamol in rats induces neurofunctional alterations in the progeny.
Sign Up to like & getrecommendations! Published in 2019 at "Neurotoxicology and teratology"
DOI: 10.1016/j.ntt.2019.106838
Abstract: Paracetamol (PAR) is an over-the-counter medicine used as analgesic or antipyretic by 40-50% of the pregnant women in different countries. Epidemiologic studies have been associating maternal use of PAR with neurodevelopmental disruption and special attention… read more here.
Keywords: par; gestational exposure; paracetamol rats; exposure paracetamol ... See more keywords
Functional and Proteomic Alterations of F1 Capacitated Spermatozoa of Adult Mice Following Gestational Exposure to Bisphenol A.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of proteome research"
DOI: 10.1021/acs.jproteome.7b00668
Abstract: Studies regarding bisphenol A (BPA) exposure and male (in)fertility have conventionally focused on modifications in ejaculated spermatozoa function from exposed individuals. However, mammalian spermatozoa are incapable of fertilization prior to achieving capacitation, the penultimate step… read more here.
Keywords: capacitated spermatozoa; spermatozoa adult; bpa; gestational exposure ... See more keywords
Gestational exposure to chlordecone promotes transgenerational changes in the murine reproductive system of males
Sign Up to like & getrecommendations! Published in 2018 at "Scientific Reports"
DOI: 10.1038/s41598-018-28670-w
Abstract: Environmental factors can affect epigenetic events during germline reprogramming and impose distinctive transgenerational consequences onto the offspring. In this study, we examined the transgenerational effects of chlordecone (CD), an organochlorine insecticide with well-known estrogenic properties.… read more here.
Keywords: chlordecone promotes; gestational exposure; transgenerational changes; changes murine ... See more keywords
Gestational exposure to silver nanoparticles enhances immune adaptation and protection against streptozotocin-induced diabetic nephropathy in mice offspring
Sign Up to like & getrecommendations! Published in 2022 at "Nanotoxicology"
DOI: 10.1080/17435390.2022.2098863
Abstract: Abstract Silver nanoparticles (AgNPs) possess unique antimicrobial properties. As a result, they are being increasingly used in a wide range of applications. Several studies have shown detrimental effects of AgNPs exposure, including inflammation, accumulation, and… read more here.
Keywords: streptozotocin induced; streptozotocin; gestational exposure; agnps exposure ... See more keywords
Repeated gestational exposure to diesel engine exhaust affects the fetal olfactory system and alters olfactory-based behavior in rabbit offspring
Sign Up to like & getrecommendations! Published in 2018 at "Particle and Fibre Toxicology"
DOI: 10.1186/s12989-018-0288-7
Abstract: BackgroundAirborne pollution, especially from diesel exhaust (DE), is known to have a negative effect on the central nervous system in exposed human populations. However, the consequences of gestational exposure to DE on the fetal brain… read more here.
Keywords: fetal olfactory; system; gestational exposure; exposure ... See more keywords
Gestational Exposure to Cigarette Smoke Suppresses the Gasotransmitter H2S Biogenesis and the Effects Are Transmitted Transgenerationally
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2020.01628
Abstract: Rationale: Gestational cigarette smoke (CS) impairs lung angiogenesis and alveolarization, promoting transgenerational development of asthma and bronchopulmonary dysplasia (BPD). Hydrogen sulfide (H2S), a proangiogenic, pro-alveolarization, and anti-asthmatic gasotransmitter is synthesized by cystathionine-γ-lyase (CSE), cystathionine-β-synthase (CBS),… read more here.
Keywords: gestational exposure; cigarette smoke; cse cbs; effects transmitted ... See more keywords
Gestational Exposure to Phthalates and Phthalate Replacements in Relation to Neurodevelopmental Delays in Early Childhood
Sign Up to like & getrecommendations! Published in 2022 at "Toxics"
DOI: 10.3390/toxics11010065
Abstract: Phthalates have been linked to changes in child neurodevelopment. However, sex-specificity has been reported inconsistently, and little is known about the impact of recent phthalate replacement chemicals. Our analysis included mother–child pairs (N = 274)… read more here.
Keywords: phthalates phthalate; gestational exposure; age; exposure phthalates ... See more keywords