Impact of gestational low-protein intake on embryonic kidney microRNA expression and in nephron progenitor cells of the male fetus.
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DOI: 10.1371/journal.pone.0246289
Abstract: BACKGROUND Here, we have demonstrated that gestational low-protein (LP) intake offspring present lower birth weight, reduced nephron numbers, renal salt excretion, arterial hypertension, and renal failure development compared to regular protein (NP) intake rats in… read more here.
Keywords: gestational low; low protein; expression; involved proliferation ... See more keywords
Gestational Low Protein Diet Modulation on miRNA Transcriptome and Its Target During Fetal and Breastfeeding Nephrogenesis
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DOI: 10.3389/fphys.2021.648056
Abstract: Background The kidney ontogenesis is the most structurally affected by gestational protein restriction, reducing 28% of their functional units. The reduced nephron number is predictive of hypertension and cardiovascular dysfunctions that are generally observed in… read more here.
Keywords: gestational low; low protein; target; protein diet ... See more keywords