Dual Antagonism of α9α10 nAChR and GABAB Receptor-Coupled CaV2.2 Channels by an Analgesic αO-Conotoxin Analogue.
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DOI: 10.1021/acs.jmedchem.3c00979
Abstract: Pain severely affects the physical and mental health of patients. The need to develop nonopioid analgesic drugs to meet medical demands is urgent. In this study, we designed a truncated analogue of αO-conotoxin, named GeX-2,… read more here.
Keywords: conotoxin; gex; gabab receptor; cav2 channels ... See more keywords