Differences Between Plasma and Cerebrospinal Fluid Glial Fibrillary Acidic Protein Levels Across the Alzheimer Disease Continuum.
Sign Up to like & getrecommendations! Published in 2021 at "JAMA neurology"
DOI: 10.1001/jamaneurol.2021.3671
Abstract: Importance Glial fibrillary acidic protein (GFAP) is a marker of reactive astrogliosis that increases in the cerebrospinal fluid (CSF) and blood of individuals with Alzheimer disease (AD). However, it is not known whether there are… read more here.
Keywords: mean; gfap levels; pathology; csf gfap ... See more keywords
Neurochemical regulation of the expression and function of glial fibrillary acidic protein in astrocytes
Sign Up to like & getrecommendations! Published in 2019 at "Glia"
DOI: 10.1002/glia.23734
Abstract: Glial fibrillary acidic protein (GFAP), a type III intermediate filament, is a marker of mature astrocytes. The expression of GFAP gene is regulated by many transcription factors (TFs), mainly Janus kinase‐2/signal transducer and activator of… read more here.
Keywords: fibrillary acidic; acidic protein; expression; glial fibrillary ... See more keywords
Glial fibrillary acidic protein promoter determines transgene expression in satellite glial cells following intraganglionic adeno‐associated virus delivery in adult rats
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Neuroscience Research"
DOI: 10.1002/jnr.24183
Abstract: Recombinant adeno‐associated viral (AAV)‐mediated therapeutic gene transfer to dorsal root ganglia (DRG) is an effective and safe tool for treating chronic pain. However, AAV with various constitutively active promoters leads to transgene expression predominantly to… read more here.
Keywords: cmv; expression; promoter; transduction ... See more keywords
Plasma autoantibodies to glial fibrillary acidic protein (GFAP) react with brain areas according to Braak staging of Parkinson’s disease
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Neural Transmission"
DOI: 10.1007/s00702-022-02495-4
Abstract: Idiopathic Parkinson’s disease (PD) is characterized by a progredient degeneration of the brain, starting at deep subcortical areas such as the dorsal motor nucleus of the glossopharyngeal and vagal nerves (DM) (stage 1), followed by… read more here.
Keywords: brain areas; parkinson disease; gfap; brain ... See more keywords
S100B, GFAP, UCH-L1 and NSE as predictors of abnormalities on CT imaging following mild traumatic brain injury: a systematic review and meta-analysis of diagnostic test accuracy
Sign Up to like & getrecommendations! Published in 2021 at "Neurosurgical Review"
DOI: 10.1007/s10143-021-01678-z
Abstract: Biomarkers such as calcium channel binding protein S100 subunit beta (S100B), glial fibrillary acidic protein (GFAP), ubiquitin c-terminal hydrolase L1 (UCH-L1) and neuron-specific enolase (NSE) have been proposed to aid in screening patients presenting with… read more here.
Keywords: sensitivity; mild traumatic; s100b; gfap ... See more keywords
The cysteine residue of glial fibrillary acidic protein is a critical target for lipoxidation and required for efficient network organization
Sign Up to like & getrecommendations! Published in 2018 at "Free Radical Biology and Medicine"
DOI: 10.1016/j.freeradbiomed.2018.04.007
Abstract: ABSTRACT The type III intermediate filament protein glial fibrillary acidic protein (GFAP) contributes to the homeostasis of astrocytes, where it co‐polymerizes with vimentin. Conversely, alterations in GFAP assembly or degradation cause intracellular aggregates linked to… read more here.
Keywords: cysteine; fibrillary acidic; acidic protein; glial fibrillary ... See more keywords
Astrocytic damage in glial fibrillary acidic protein astrocytopathy during initial attack.
Sign Up to like & getrecommendations! Published in 2019 at "Multiple sclerosis and related disorders"
DOI: 10.1016/j.msard.2019.01.036
Abstract: OBJECTIVE Determination of glial fibrillary acidic protein (GFAP), aquaporin 4 (AQP4), and myelin oligodendrocyte glycoprotein (MOG) levels in cerebrospinal fluid (CSF), and astrocytic damage analysis in patients with GFAP astrocytopathy (GFAP-A) and other conditions. METHODS… read more here.
Keywords: csf gfap; astrocytopathy patients; gfap astrocytopathy; damage ... See more keywords
Comparison of effects of high- and low-frequency electromagnetic fields on proliferation and differentiation of neural stem cells
Sign Up to like & getrecommendations! Published in 2021 at "Neuroscience Letters"
DOI: 10.1016/j.neulet.2020.135463
Abstract: To compare the effects of high- (HF-EMF) and low-frequency electromagnetic fields (LF-EMF) on the proliferation and differentiation of neural stem cells (NSCs). NSCs were obtained from SD rat hippocampus and cultured in suspension and adherent… read more here.
Keywords: effects high; frequency electromagnetic; proliferation; differentiation ... See more keywords
Astrogliosis and episodic memory in late life: higher GFAP is related to worse memory and white matter microstructure in healthy aging and Alzheimer's disease
Sign Up to like & getrecommendations! Published in 2021 at "Neurobiology of Aging"
DOI: 10.1016/j.neurobiolaging.2021.02.012
Abstract: Astrocytes play a formative role in memory consolidation during physiological conditions; when dysregulated, astrocytes release glial fibrillary acidic protein (GFAP), which has been linked with negative memory outcomes in animal studies. We examined the association… read more here.
Keywords: memory white; pathology; memory; gfap ... See more keywords
GFAp and tau protein as predictors of neurological outcome after out-of-hospital cardiac arrest: A post hoc analysis of the COMACARE trial
Sign Up to like & getrecommendations! Published in 2021 at "Resuscitation"
DOI: 10.1016/j.resuscitation.2021.11.033
Abstract: Aim To determine the ability of serum glial fibrillary acidic protein (GFAp) and tau protein to predict neurological outcome after out-of-hospital cardiac arrest (OHCA). Methods We measured plasma concentrations of GFAp and tau of patients… read more here.
Keywords: tau protein; gfap; gfap tau; trial ... See more keywords
Glial Fibrillary Acidic Protein (GFAP) Outperforms S100 Calcium-Binding Protein B (S100B) and Ubiquitin C-Terminal Hydrolase L1 (UCH-L1) as Predictor for Positive Computed Tomography of the Head in Trauma Subjects.
Sign Up to like & getrecommendations! Published in 2019 at "World neurosurgery"
DOI: 10.1016/j.wneu.2019.04.170
Abstract: OBJECTIVE Traumatic brain injuries (TBIs) are largely underdiagnosed and may have persistent refractory consequences. Current assessments for acute TBI are limited to physical examination and imaging. Biomarkers such as glial fibrillary acidic protein (GFAP), ubiquitin… read more here.
Keywords: protein; head; uch s100b; trauma ... See more keywords