GFPT1 promotes the proliferation of cervical cancer via regulating the ubiquitination and degradation of PTEN.
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DOI: 10.1093/carcin/bgac073
Abstract: Cervical cancer demonstrates the fourth incidence and death rate in female worldwide. Glutamine--fructose-6-phosphate transaminase 1 (GFPT1), the first rate-limited enzyme of hexosamine biosynthesis pathway, has been reported to promote the progression of cancers. However, the… read more here.
Keywords: cervical cancer; proliferation cervical; ubiquitination degradation; gfpt1 ... See more keywords