Articles with "gga1 regulates" as a keyword



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GGA1 regulates signal-dependent sorting of BACE1 to recycling endosomes, which moderates Aβ production

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Published in 2018 at "Molecular Biology of the Cell"

DOI: 10.1091/mbc.e17-05-0270

Abstract: The diversion of the β-secretase BACE1 from the endo-lysosomal pathway to recycling endosomes is important in the regulation of amyloid beta production. Here we define BACE1 transport from early to recycling endosomes and identify essential… read more here.

Keywords: recycling endosomes; production; signal dependent; gga1 regulates ... See more keywords