Identification of two types of GGAA-microsatellites and their roles in EWS/FLI binding and gene regulation in Ewing sarcoma
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DOI: 10.1371/journal.pone.0186275
Abstract: Ewing sarcoma is a bone malignancy of children and young adults, frequently harboring the EWS/FLI chromosomal translocation. The resulting fusion protein is an aberrant transcription factor that uses highly repetitive GGAA-containing elements (microsatellites) to activate… read more here.
Keywords: binding gene; ews fli; fli binding; ggaa microsatellites ... See more keywords