Suppression of the yeast elongation factor Spt4 ortholog reduces expanded SCA36 GGCCUG repeat aggregation and cytotoxicity
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DOI: 10.1016/j.brainres.2018.12.045
Abstract: A hexanucleotide GGCCTG repeat expansion in intron 1 of the nucleolar protein 56 gene causes spinocerebellar ataxia type 36 (SCA36), which is a relatively pure cerebellar ataxia with progressive motor neuron involvement. In this study… read more here.
Keywords: repeat; ggccug; elongation factor; sca36 ... See more keywords