Protein Prenyltransferases and Their Inhibitors: Structural and Functional Characterization
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DOI: 10.3390/ijms23105424
Abstract: Protein prenylation is a post-translational modification controlling the localization, activity, and protein–protein interactions of small GTPases, including the Ras superfamily. This covalent attachment of either a farnesyl (15 carbon) or a geranylgeranyl (20 carbon) isoprenoid… read more here.
Keywords: prenyltransferases inhibitors; structural functional; inhibitors structural; ggtase ... See more keywords