Inverting family GH156 sialidases define an unusual catalytic motif for glycosidase action
Sign Up to like & getrecommendations! Published in 2019 at "Nature Communications"
DOI: 10.1038/s41467-019-12684-7
Abstract: Sialic acids are a family of related sugars that play essential roles in many biological events intimately linked to cellular recognition in both health and disease. Sialidases are therefore orchestrators of cellular biology and important… read more here.
Keywords: gh156 sialidases; family; sialidases define; family gh156 ... See more keywords
Human Gut Metagenomes Encode Diverse GH156 Sialidases
Sign Up to like & getrecommendations! Published in 2022 at "Applied and Environmental Microbiology"
DOI: 10.1128/aem.01755-22
Abstract: Sialic acids occupy terminal positions of human glycans where they act as receptors for microbes, toxins, and immune signaling molecules. Microbial enzymes that remove sialic acids, sialidases, are abundant in the human microbiome where they… read more here.
Keywords: gh156 sialidases; family; sialic acids; may contribute ... See more keywords