Exchange proteins directly activated by cAMP induce the proliferation of rat anterior pituitary GH3 cells via the activation of extracellular signal-regulated kinase.
Sign Up to like & getrecommendations! Published in 2017 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2017.02.075
Abstract: Cyclic adenosine 3'-5'-monophosphate (cAMP) plays a crucial role in regulating pituitary cell proliferation and hormone synthesis. Recent evidence suggests that exchange proteins directly activated by cAMP (Epacs) may mediate the effects of cAMP. Here we… read more here.
Keywords: camp; proliferation; gh3 cells; exchange proteins ... See more keywords
The GH3 amidosynthetases family and their role in metabolic crosstalk modulation of plant signaling compounds.
Sign Up to like & getrecommendations! Published in 2021 at "Phytochemistry"
DOI: 10.1016/j.phytochem.2021.113039
Abstract: The Gretchen Hagen 3 (GH3) genes encoding proteins belonging to the ANL superfamily are widespread in the plant kingdom. The ANL superfamily consists of three groups of adenylating enzymes: aryl- and acyl-CoA synthetases, firefly luciferase,… read more here.
Keywords: gh3; amidosynthetases family; gh3 amidosynthetases; plant ... See more keywords
Chemical genetic screening identifies nalacin as an inhibitor of GH3 amido synthetase for auxin conjugation
Sign Up to like & getrecommendations! Published in 2022 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1101/2022.05.29.493926
Abstract: Root system is critical for plant growth and development. To develop plant growth regulators functioning in root development, we performed a phenotype-based chemical screen in Arabidopsis and identified a chemical, nalacin, that mimicked the effects… read more here.
Keywords: amido; identifies nalacin; development; inhibitor ... See more keywords
Genome-wide analysis, transcription factor network approach and gene expression profile of GH3 genes over early somatic embryogenesis in Coffea spp
Sign Up to like & getrecommendations! Published in 2019 at "BMC Genomics"
DOI: 10.1186/s12864-019-6176-1
Abstract: BackgroundCoffee production relies on plantations with varieties from Coffea arabica and Coffea canephora species. The first, the most representative in terms of coffee consumption, is mostly propagated by seeds, which leads to management problems regarding… read more here.
Keywords: early somatic; embryogenesis; somatic embryogenesis; transcription factor ... See more keywords
Crystal Structure of a GH3 beta-Glucosidase from the Thermophilic FungusChaetomium thermophilum.
Sign Up to like & getrecommendations! Published in 2019 at "International Journal of Molecular Sciences"
DOI: 10.2210/pdb6sz6/pdb
Abstract: Beta-glucosidases (β-glucosidases) have attracted considerable attention in recent years for use in various biotechnological applications. They are also essential enzymes for lignocellulose degradation in biofuel production. However, cost-effective biomass conversion requires the use of highly… read more here.
Keywords: glucosidase thermophilic; beta; gh3; structure ... See more keywords
Fulvestrant inhibits the glycolysis of prolactinoma GH3 cells by downregulating IRE1/XBP1 signaling pathway.
Sign Up to like & getrecommendations! Published in 2018 at "European review for medical and pharmacological sciences"
DOI: 10.26355/eurrev_201808_15739
Abstract: OBJECTIVE We aimed to evaluate the effects of fulvestrant on the glycolysis of prolactinoma GH3 cells, and reveal the potential regulatory mechanisms. MATERIALS AND METHODS Prolactinoma cell line GH3 was treated with different concentrations of… read more here.
Keywords: xbp1s xbp1u; gh3 cells; cells downregulating; prolactinoma gh3 ... See more keywords
Genome-Wide Identification of Auxin-Responsive GH3 Gene Family in Saccharum and the Expression of ScGH3-1 in Stress Response
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms232112750
Abstract: Gretchen Hagen3 (GH3), one of the three major auxin-responsive gene families, is involved in hormone homeostasis in vivo by amino acid splicing with the free forms of salicylic acid (SA), jasmonic acid (JA) or indole-3-acetic… read more here.
Keywords: gene; family; ssgh3; gene family ... See more keywords