Abstract 3401: Discovery of GH658, a novel tead allosteric inhibitor as a cancer therapy
Sign Up to like & getrecommendations! Published in 2023 at "Cancer Research"
DOI: 10.1158/1538-7445.am2023-3401
Abstract: The Hippo pathway is an evolutionarily conserved signaling cascade. Its dysregulation may lead to cancer progression, metastasis, cancer therapy resistance, and immune evasion. Diverse genetic aberrations leading to YAP/TAZ hyperactivation have been elucidated over the… read more here.
Keywords: tead; gh658; gh658 novel; cancer therapy ... See more keywords