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   Articles with "ghr" as a keyword



The inhibition of GHR enhanced cytotoxic effects of etoposide on neuroblastoma.

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recommendations! Published in 2021 at "Cellular signalling"

DOI: 10.1016/j.cellsig.2021.110081

Abstract: Etoposide, a DNA damage-inducing agent, is widely used to treat neuroblastoma. Etoposide binds to and inhibits topoisomerase II, thereby inducing the DNA damage response. However, the underlying mechanism of etoposide resistance in neuroblastoma remains unclear.… read more here.

Keywords: cell viability; effects etoposide; etoposide resistance; neuroblastoma ... See more keywords
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Cholinergic neurons in the hypothalamus and dorsal motor nucleus of the vagus are directly responsive to growth hormone.

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recommendations! Published in 2020 at "Life sciences"

DOI: 10.1016/j.lfs.2020.118229

Abstract: AIMS Cholinergic neurons are distributed in brain areas containing growth hormone (GH)-responsive cells. We determined if cholinergic neurons are directly responsive to GH and the metabolic consequences of deleting the GH receptor (GHR) specifically in… read more here.

Keywords: nucleus; dorsal motor; cholinergic neurons; growth hormone ... See more keywords
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Heterogeneity of Growth Hormone Receptor Expression in Craniopharyngioma - Implications for Surgical Strategy.

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recommendations! Published in 2020 at "World neurosurgery"

DOI: 10.1016/j.wneu.2020.02.022

Abstract: BACKGROUND Recent molecular investigations for craniopharyngiomas have investigated possible predictive biological markers. Growth hormone receptor (GHR) is thought to be involved in tumor aggressiveness, and high expression of GHR is associated with shorter duration of… read more here.

Keywords: growth hormone; expression; ghr; tumor ... See more keywords

Studying the pathogenic Streptomyces strains responsible for causing potato common scab in Iran and assessing the efficacy of native S. fimicarius-ghR and S. rochei-FsG in reducing scab lesion development in both potato and radish hosts in vivo

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recommendations! Published in 2024 at "Biocontrol Science and Technology"

DOI: 10.1080/09583157.2024.2363407

Abstract: ABSTRACT Potato common scab an important widespread disease caused by Streptomyces species, usually can diminish the market value of tubers. None of the disease management methods is considered efficient. Non-pathogenic Streptomyces species owing to their… read more here.

Keywords: potato; ghr; potato common; fsg ... See more keywords

Identification of polymorphic loci in OSMR and GHR genes and analysis of their association with growth traits in sheep.

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recommendations! Published in 2022 at "Animal biotechnology"

DOI: 10.1080/10495398.2022.2105227

Abstract: The aim of this study was to analyze the effect of OSMR and GHR genes polymorphisms on growth traits in sheep. The single nucleotide polymorphisms of sheep OSMR and GHR genes were identified by DNA… read more here.

Keywords: osmr ghr; traits sheep; ghr; growth traits ... See more keywords

Characterisation of dominant-negative GH receptor variants reveals a potential therapeutic target for short stature.

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recommendations! Published in 2023 at "European journal of endocrinology"

DOI: 10.1093/ejendo/lvad039

Abstract: OBJECTIVE Growth hormone insensitivity (GHI) encompasses growth restriction, normal/elevated growth hormone (GH), and low insulin-like growth factor I (IGF1). 'Non-classical' GHI is poorly characterised and is rarely caused by heterozygous dominant-negative (DN) variants located in… read more here.

Keywords: growth restriction; ghr; growth; ghr variants ... See more keywords

Nonlinear association between gamma-glutamyl transferase to high-density lipoprotein cholesterol ratio and risk of progression from normoglycemia to prediabetes: a 5-year cohort study

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recommendations! Published in 2025 at "Frontiers in Endocrinology"

DOI: 10.3389/fendo.2025.1552044

Abstract: Objective Current research on the association between the Gamma-glutamyl transferase to high-density lipoprotein ratio (GHR) and the risk of prediabetes (pre-DM) remains scarce. This study aims to explore the potential link between GHR and the… read more here.

Keywords: progression normoglycemia; ghr; risk; association ... See more keywords

Identification of the cDNA Encoding the Growth Hormone Receptor (GHR) and the Regulation of GHR and IGF-I Gene Expression by Nutritional Status in Reeves’ Turtle (Chinemys reevesii)

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recommendations! Published in 2020 at "Frontiers in Genetics"

DOI: 10.3389/fgene.2020.00587

Abstract: Chinemys reevesii (Reeves’ turtle) is a slow-growing reptile that is distributed widely across China. Prior to this study, the cDNA sequence of the growth hormone receptor (GHR) in the Reeve’s turtle, or how periods of… read more here.

Keywords: reeves turtle; cdna; expression; ghr ... See more keywords

Correlation between gallstones and fasting blood glucose to serum high-density lipoprotein cholesterol ratio among American adults

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recommendations! Published in 2025 at "Frontiers in Medicine"

DOI: 10.3389/fmed.2025.1528613

Abstract: Background Research indicates that the ratio of fasting blood glucose (FBG) to serum high-density lipoprotein cholesterol (HDL-C) (GHR) can accurately predict many diseases. Nevertheless, the relationship between GHR and the risk of gallbladder stones remains… read more here.

Keywords: ghr; gallbladder stones; blood glucose; fasting blood ... See more keywords

Gender Specificity and Local Socioeconomic Influence on Association of GHR fl/d3 Polymorphism With Growth and Metabolism in Children and Adolescents

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recommendations! Published in 2022 at "Frontiers in Pediatrics"

DOI: 10.3389/fped.2022.546080

Abstract: Objective Growth hormone receptor (GHR) mediates most GH biological actions. This study is aimed to evaluate whether GHR fl/d3 polymorphism contributes to the inter-individual variability of growth and metabolism in healthy children and adolescents. Methods… read more here.

Keywords: ghr; ghr polymorphism; growth metabolism; hypertension ... See more keywords

Immunohistochemical Characterization of PepT1 and Ghrelin in Gastrointestinal Tract of Zebrafish: Effects of Spirulina Vegetarian Diet on the Neuroendocrine System Cells After Alimentary Stress

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recommendations! Published in 2018 at "Frontiers in Physiology"

DOI: 10.3389/fphys.2018.00614

Abstract: Gastrointestinal function in vertebrates is influenced by stressors, such as fasting and refeeding, different types of diet and hormonal factors. The aim of this paper was to analyze the effect of a Spirulina (Arthrospira platensis)… read more here.

Keywords: gastrointestinal tract; pept1 ghrelin; tract; tract zebrafish ... See more keywords