Explainable Machine Learning Models to Predict Gibbs–Donnan Effect During Ultrafiltration and Diafiltration of High‐Concentration Monoclonal Antibody Formulations
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DOI: 10.1002/biot.202400212
Abstract: Evaluating the Gibbs–Donnan and volume exclusion effects during protein ultrafiltration and diafiltration (UF/DF) is crucial in biopharmaceutical process development to precisely control the concentration of the drug substance in the final formulation. Understanding the interactions… read more here.
Keywords: ultrafiltration diafiltration; gibbs donnan; donnan; predict gibbs ... See more keywords