A novel Thioredoxin-related protein 14 from Fasciola gigantica has an immunodiagnostic potential for fasciolosis.
Sign Up to like & getrecommendations! Published in 2020 at "Acta tropica"
DOI: 10.1016/j.actatropica.2020.105471
Abstract: In the definitive host, a trematode parasite can survive and evade the damage by reactive oxygen species that are generated from its metabolism and the host immune cells. Several anti-oxidant proteins are found in Fasciola… read more here.
Keywords: fasciola; gigantica; thioredoxin related; thioredoxin ... See more keywords
Development of multi-epitope driven subunit vaccine against Fasciola gigantica using immunoinformatics approach.
Sign Up to like & getrecommendations! Published in 2019 at "International journal of biological macromolecules"
DOI: 10.1016/j.ijbiomac.2019.07.024
Abstract: Fascioliasis, a serious helminth disease of the livestock population, results from infection with the parasite Fasciola. Despite the alarming increase in drug resistance, a safe and fully effective vaccine for fascioliasis is still not available.… read more here.
Keywords: fasciola; gigantica; subunit vaccine; vaccine ... See more keywords
Molecular characterization and phylogenetic analysis of Fasciola gigantica from Nigeria.
Sign Up to like & getrecommendations! Published in 2017 at "Parasitology international"
DOI: 10.1016/j.parint.2016.10.010
Abstract: Fasciola gigantica is considered the major pathogen causing fasciolosis in Africa; however, molecular characterization of this fluke has not been adequately elucidated. It is important to scientifically elucidate the dispersal history of F. gigantica by… read more here.
Keywords: molecular characterization; fasciola; gigantica; fasciola gigantica ... See more keywords
Genetic diversity and multiplicity of infection in Fasciola gigantica isolates of Pakistani livestock.
Sign Up to like & getrecommendations! Published in 2020 at "Parasitology international"
DOI: 10.1016/j.parint.2020.102071
Abstract: Fasciola spp. are responsible for over 3 billion US dollars of production loss annually in livestock and cause widespread zoonotic disease. Nevertheless, understating of the emergence and spread of the trematode species is poor. The… read more here.
Keywords: multiplicity; fasciola; gigantica; genetic diversity ... See more keywords
Assessing the performance of a Fasciola gigantica serum antibody ELISA to estimate prevalence in cattle in Cameroon
Sign Up to like & getrecommendations! Published in 2019 at "BMC Veterinary Research"
DOI: 10.1186/s12917-018-1762-z
Abstract: BackgroundCattle rearing in Cameroon is both economically and culturally important, however parasitic diseases detrimentally impact cattle productivity. In sub-Saharan Africa bovine fasciolosis is generally attributed to F. gigantica, although understanding of Fasciola species present and… read more here.
Keywords: fasciola; gigantica; antibody elisa; performance ... See more keywords
Transcriptomic landscape of hepatic lymph nodes, peripheral blood lymphocytes and spleen of swamp buffaloes infected with the tropical liver fluke Fasciola gigantica
Sign Up to like & getrecommendations! Published in 2022 at "PLoS Neglected Tropical Diseases"
DOI: 10.1371/journal.pntd.0010286
Abstract: The tropical liver fluke Fasciola gigantica is a parasitic helminth that has been frequently reported to infect mammals, typically involving water buffaloes. In this study, we characterized the tissue transcriptional landscape of buffaloes following infection… read more here.
Keywords: tropical liver; fluke fasciola; hepatic lymph; fasciola gigantica ... See more keywords
Seroprevalence of Fasciola gigantica infection in bovines using cysteine proteinase dot enzyme-linked immunosorbent assay
Sign Up to like & getrecommendations! Published in 2017 at "Veterinary World"
DOI: 10.14202/vetworld.2017.1189-1193
Abstract: Aim: The objective of the present study was to know the seroprevalence status of Fasciola gigantica infection in cattle and buffaloes using cysteine proteinase (CP) antigen in dot enzyme-linked immunosorbent assay (ELISA) format under field… read more here.
Keywords: dot; gigantica; infection; fasciola gigantica ... See more keywords
Cloning and Expression of Fasciola gigantica Cathepsin-B Recombinant Proteins
Sign Up to like & getrecommendations! Published in 2020 at "Indian Journal of Animal Research"
DOI: 10.18805/ijar.b-3959
Abstract: Fasciola gigantica cathepsin (cysteine) proteases are potential diagnostic antigens for animal and human fasciolosis. These include cathepsin-L proteases that have been exploited in the diagnosis of animal fasciolosis. However, no scientific data on the diagnostic… read more here.
Keywords: gigantica cathepsin; gigantica; cathepsin; fasciola gigantica ... See more keywords
Paleobiogeographical origins of Fasciola hepatica and F. gigantica in light of new DNA sequence characteristics of F. nyanzae from hippopotamus
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Veterinary Science"
DOI: 10.3389/fvets.2022.990872
Abstract: Fascioliasis is a highly pathogenic disease affecting humans and livestock worldwide. It is caused by the liver flukes Fasciola hepatica transmitted by Galba/Fossaria lymnaeid snails in Europe, Asia, Africa, the Americas and Oceania, and F.… read more here.
Keywords: fasciola hepatica; hepatica; dna; gigantica ... See more keywords
Exploiting Comparative Omics to Understand the Pathogenic and Virulence-Associated Protease: Anti-Protease Relationships in the Zoonotic Parasites Fasciola hepatica and Fasciola gigantica
Sign Up to like & getrecommendations! Published in 2022 at "Genes"
DOI: 10.3390/genes13101854
Abstract: The helminth parasites, Fasciola hepatica and Fasciola gigantica, are the causative agents of fasciolosis, a global and economically important disease of people and their livestock. Proteases are pivotal to an array of biological processes related… read more here.
Keywords: fasciola hepatica; hepatica fasciola; protease; gigantica ... See more keywords
Potential Hybridization of Fasciola hepatica and F. gigantica in Africa—A Scoping Review
Sign Up to like & getrecommendations! Published in 2022 at "Pathogens"
DOI: 10.3390/pathogens11111303
Abstract: The occurrence of Fasciola gigantica and F. hepatica in Africa is well documented; however, unlike in Asia, there is a paucity of information on the existence of hybrids or parthenogenetic species on the continent. Nonetheless,… read more here.
Keywords: gigantica; hepatica gigantica; fasciola; fasciola hybrids ... See more keywords