Translational repression of NMD targets by GIGYF2 and EIF4E2.
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DOI: 10.1371/journal.pgen.1009813
Abstract: Translation of messenger RNAs (mRNAs) with premature termination codons produces truncated proteins with potentially deleterious effects. This is prevented by nonsense-mediated mRNA decay (NMD) of these mRNAs. NMD is triggered by ribosomes terminating upstream of… read more here.
Keywords: gigyf2 eif4e2; targets gigyf2; translational repression; nmd targets ... See more keywords