LAUSR

About LAUSR
Donate
Contact Us

Follow us:

You are not signed in:

Sign Up!


   Articles with "gilford progeria" as a keyword



Hutchinson-Gilford Progeria Syndrome.

Sign Up to like & get
recommendations! Published in 2025 at "JAMA dermatology"

DOI: 10.1001/jamadermatol.2025.0793

Abstract: This case report describes a boy younger than 2 years with Hutchinson–Gilford progeria syndrome. read more here.

Keywords: progeria syndrome; gilford progeria; dermatology; hutchinson gilford ... See more keywords

Microbiome at sites of gingival recession in children with Hutchinson–Gilford progeria syndrome

Sign Up to like & get
recommendations! Published in 2018 at "Journal of Periodontology"

DOI: 10.1002/jper.17-0351

Abstract: BACKGROUND Hutchinson-Gilford progeria syndrome (HGPS) is a rare premature aging disorder with significant oral and dental abnormalities. Clinical symptoms include various features of accelerated aging such as alopecia, loss of subcutaneous fat, bone abnormalities, and… read more here.

Keywords: hutchinson gilford; gingival recession; sites gingival; progeria syndrome ... See more keywords

Pharmacotherapy to gene editing: potential therapeutic approaches for Hutchinson–Gilford progeria syndrome

Sign Up to like & get
recommendations! Published in 2020 at "GeroScience"

DOI: 10.1007/s11357-020-00167-3

Abstract: Hutchinson–Gilford progeria syndrome (HGPS), commonly called progeria, is an extremely rare disorder that affects only one child per four million births. It is characterized by accelerated aging in affected individuals leading to premature death at… read more here.

Keywords: hgps; hutchinson gilford; disorder; therapeutic approaches ... See more keywords

Cardiovascular manifestations of Hutchinson-Gilford progeria syndrome.

Sign Up to like & get
recommendations! Published in 2022 at "Cardiology in the young"

DOI: 10.1017/s104795112200004x

Abstract: Cardiovascular complications are the most frequent cause of death in patients with the Hutchinson-Gilford progeria syndrome. However, due to its rarity, studying the course of cardiac abnormalities has been a challenge. The cardiovascular phenotype helps… read more here.

Keywords: cardiovascular manifestations; progeria syndrome; gilford progeria; hutchinson gilford ... See more keywords

The clinical characteristics of Asian patients with classical-type Hutchinson–Gilford progeria syndrome

Sign Up to like & get
recommendations! Published in 2017 at "Journal of Human Genetics"

DOI: 10.1038/jhg.2017.90

Abstract: Hutchinson–Gilford progeria syndrome (HGPS) is an extremely rare genetic disorder that shows a characteristic progeria phenotype. We conducted a questionnaire survey of 1173 tertiary hospitals in Japan and reviewed the academic reports, to identify the… read more here.

Keywords: hutchinson gilford; characteristics asian; asian patients; progeria syndrome ... See more keywords
Photo by nci from unsplash

An overview of treatment strategies for Hutchinson-Gilford Progeria syndrome

Sign Up to like & get
recommendations! Published in 2018 at "Nucleus"

DOI: 10.1080/19491034.2018.1460045

Abstract: ABSTRACT Hutchinson-Gilford progeria syndrome (HGPS) is a sporadic, autosomal dominant disorder characterized by premature and accelerated aging symptoms leading to death at the mean age of 14.6 years usually due to cardiovascular complications. HGPS is… read more here.

Keywords: hutchinson gilford; treatment strategies; overview treatment; progeria syndrome ... See more keywords

Transcriptional profiling of Hutchinson-Gilford Progeria syndrome fibroblasts reveals deficits in mesenchymal stem cell commitment to differentiation related to early events in endochondral ossification

Sign Up to like & get
recommendations! Published in 2022 at "eLife"

DOI: 10.1101/2022.06.21.497024

Abstract: Hutchinson-Gilford Progeria Syndrome results from a mutation in Lamin A, and it is characterized by the incorporation of progerin into the nuclear lamina. Progerin expression leads to alterations in genome architecture, nuclear morphology, and epigenetic… read more here.

Keywords: endochondral ossification; progeria syndrome; gilford progeria; hutchinson gilford ... See more keywords

Lysophosphatidic acid receptor LPA3 prevents oxidative stress and cellular senescence in Hutchinson–Gilford progeria syndrome

Sign Up to like & get
recommendations! Published in 2019 at "Aging Cell"

DOI: 10.1111/acel.13064

Abstract: Hutchinson–Gilford progeria syndrome (HGPS) is a rare laminopathy that produces a mutant form of prelamin A, known as Progerin, resulting in premature aging. HGPS cells show morphological abnormalities of the nuclear membrane, reduced cell proliferation… read more here.

Keywords: hutchinson gilford; senescence; progeria syndrome; lysophosphatidic acid ... See more keywords

DNA methylation signatures in Blood DNA of Hutchinson–Gilford Progeria syndrome

Sign Up to like & get
recommendations! Published in 2022 at "Aging Cell"

DOI: 10.1111/acel.13555

Abstract: Hutchinson–Gilford Progeria Syndrome (HGPS) is an extremely rare genetic disorder caused by mutations in the LMNA gene and characterized by premature and accelerated aging beginning in childhood. In this study, we performed the first genome‐wide… read more here.

Keywords: methylation; dna; gilford progeria; hutchinson gilford ... See more keywords

Mitophagy defect mediates the aging‐associated hallmarks in Hutchinson–Gilford progeria syndrome

Sign Up to like & get
recommendations! Published in 2024 at "Aging Cell"

DOI: 10.1111/acel.14143

Abstract: Hutchinson–Gilford progeria syndrome (HGPS) is a rare and fatal disease manifested by premature aging and aging‐related phenotypes, making it a disease model for aging. The cellular machinery mediating age‐associated phenotypes in HGPS remains largely unknown,… read more here.

Keywords: hgps; aging associated; progeria syndrome; mitophagy ... See more keywords

Patient‐Derived Cortical Organoids Reveal Senescence of Neural Progenitor Cells in Hutchinson‐Gilford Progeria Syndrome

Sign Up to like & get
recommendations! Published in 2025 at "Aging Cell"

DOI: 10.1111/acel.70143

Abstract: Hutchinson‐Gilford progeria syndrome (HGPS) is a rare genetic disorder characterized by premature aging and primarily caused by the accumulation of progerin, a mutant form of lamin A. Although the effects of progerin on multiple tissues… read more here.

Keywords: progeria syndrome; gilford progeria; hutchinson gilford; development ... See more keywords