A human case of GIMAP6 deficiency: a novel primary immune deficiency
Sign Up to like & getrecommendations! Published in 2020 at "European Journal of Human Genetics"
DOI: 10.1038/s41431-020-00773-x
Abstract: The GTPase of immunity-associated proteins (GIMAPs) are a family of genes believed to contribute to lymphocyte development, signaling, and apoptosis, thus playing an important role in immune system homeostasis. While models of gene derangement have… read more here.
Keywords: gimap6 gene; gimap6 protein; human case; deficiency ... See more keywords
GIMAP6 is required for T cell maintenance and efficient autophagy in mice
Sign Up to like & getrecommendations! Published in 2018 at "PLoS ONE"
DOI: 10.1371/journal.pone.0196504
Abstract: The GTPases of the immunity-associated proteins (GIMAP) GTPases are a family of proteins expressed strongly in the adaptive immune system. We have previously reported that in human cells one member of this family, GIMAP6, interacts… read more here.
Keywords: gimap6 required; maintenance; immune system; mice ... See more keywords