Lack of pathogenic mutations in SOS1 gene in phenytoin-induced gingival overgrowth patients.
Sign Up to like & getrecommendations! Published in 2017 at "Archives of oral biology"
DOI: 10.1016/j.archoralbio.2017.04.002
Abstract: OBJECTIVE Gingival overgrowth is a side effect associated with some distinct classes of drugs, such as anticonvulsants, immunosuppressants, and calcium channel blockers. One of the main drugs associated with gingival overgrowth is the antiepileptic phenytoin,… read more here.
Keywords: sos1 gene; gingival overgrowth; phenytoin; overgrowth ... See more keywords
Does systemically administered azithromycin have an effect on gingival overgrowth? A systematic review.
Sign Up to like & getrecommendations! Published in 2019 at "Oral surgery, oral medicine, oral pathology and oral radiology"
DOI: 10.1016/j.oooo.2019.07.022
Abstract: OBJECTIVE The aim of this systematic review was to evaluate studies that analyzed the effect of systemically administered azithromycin (AZM) on cyclosporine A (CsA)-mediated gingival overgrowth (GO). STUDY DESIGN A systematic literature search was performed… read more here.
Keywords: systemically administered; administered azithromycin; systematic review; effect ... See more keywords
Biallelic frameshift variant in the TBC1D2B gene in two siblings with progressive gingival overgrowth, fibrous dysplasia of face, and mental deterioration
Sign Up to like & getrecommendations! Published in 2022 at "Clinical Genetics"
DOI: 10.1111/cge.14215
Abstract: Biallelic loss‐of‐function variants in the TBC1D2B gene were recently reported as a cause of a neurodevelopmental disorder with seizures and gingival overgrowth. Here, we report two male siblings with the similar clinical characteristics. They started… read more here.
Keywords: tbc1d2b gene; mental deterioration; fibrous dysplasia; gingival overgrowth ... See more keywords
Cyclosporine‐induced gingival overgrowth—Review
Sign Up to like & getrecommendations! Published in 2022 at "Dermatologic Therapy"
DOI: 10.1111/dth.15912
Abstract: Drug‐induced gingival overgrowth (DIGO) is an undesirable effect resulting from the therapy of one of the three groups of drugs: phenytoin, calcium channel blockers, and cyclosporine A (CsA). It is caused by a fibrous overgrowth… read more here.
Keywords: gingival overgrowth; cyclosporine induced; induced gingival; review ... See more keywords
Cyclosporine A-induced gingival overgrowth in renal transplant patients accompanied by epithelial-to-mesenchymal transition.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of periodontal research"
DOI: 10.1111/jre.13115
Abstract: OBJECTIVE To investigate the association between the prevalence of cyclosporin A-induced gingival overgrowth and the expression of the epithelial-to-mesenchymal transition factors in the gingival tissues of renal transplant patients. BACKGROUND Gingival overgrowth (GO) is a… read more here.
Keywords: gingival overgrowth; transplant patients; induced gingival; csa ... See more keywords
Phenytoin-induced gingival overgrowth caused by death receptor pathway malfunction.
Sign Up to like & getrecommendations! Published in 2017 at "Oral diseases"
DOI: 10.1111/odi.12651
Abstract: OBJECTIVE In this study, we investigated the role of phenytoin (PHT) in death receptor-induced apoptosis of gingival fibroblasts to clarify the mechanism of PHT-induced gingival overgrowth. METHODS Human gingival fibroblasts were cultured to semiconfluence and… read more here.
Keywords: pht; death receptor; induced gingival; gingival fibroblasts ... See more keywords
Therapeutic potential of proteasome inhibitors for dihydropyridine-induced gingival overgrowth.
Sign Up to like & getrecommendations! Published in 2019 at "Oral diseases"
DOI: 10.1111/odi.13260
Abstract: OBJECTIVES NF-κB plays a crucial role in collagen overproduction in dihydropyridine-induced gingival overgrowth (DIGO) fibroblasts. We aim to investigate the role of the kappa B (IκB) kinase (IKK)-NF-κB pathway and downstream collagen type I (Col… read more here.
Keywords: proteasome inhibitors; induced gingival; digo cells; dihydropyridine induced ... See more keywords
The multifactorial aetiology of gingival overgrowth: a case report illustrating diagnosis and management
Sign Up to like & getrecommendations! Published in 2019 at "Dental Update"
DOI: 10.12968/denu.2019.46.7.662
Abstract: Gingival overgrowth is the enlargement of gingival tissues and has various underlying aetiological factors. This case report highlights the multifactorial aetiology of gingival overgrowth for a patient who was prescribed an immunosuppressive strategy following renal… read more here.
Keywords: case report; overgrowth; gingival overgrowth;
Prevention and non-surgical periodontal therapy of calcium channel blockers induced severe gingival overgrowth.
Sign Up to like & getrecommendations! Published in 2022 at "Orvosi hetilap"
DOI: 10.1556/650.2022.32385
Abstract: Összefoglaló. Bevezetés és célkitűzés: A gingivahyperplasia a kalciumcsatorna-blokkoló gyógyszerek gyakori mellékhatása. Eredményeink közlésének célja, hogy bemutassuk, sebészi terápia nélkül, megfelelő egyéni szájhigiénia kialakításával és nem sebészi parodontalis terápiával milyen eredményt tudunk elérni az ínymegnagyobbodás kezelése… read more here.
Keywords: gingival overgrowth; non surgical; calcium channel; therapy ... See more keywords
Calcium Channel Blocker-induced Gingival Overgrowth
Sign Up to like & getrecommendations! Published in 2019 at "Internal Medicine"
DOI: 10.2169/internalmedicine.0852-18
Abstract: A 69-year-old man was admitted to the hospital with bacterial pneumonia. He had previously been diagnosed with mild hypertension and treated with oral calcium channel blockers for six months. He denied any history of an… read more here.
Keywords: calcium channel; channel; induced gingival; gingival overgrowth ... See more keywords
Systematic review of cyclosporin A-induced gingival overgrowth and genetic predisposition.
Sign Up to like & getrecommendations! Published in 2017 at "Quintessence international"
DOI: 10.3290/j.qi.a38120
Abstract: OBJECTIVE This systematic review aimed to investigate the influence of gene polymorphisms on the development of gingival overgrowth in renal transplant patients treated with cyclosporin A. METHOD AND MATERIALS Electronic and hand literature searches were… read more here.
Keywords: systematic review; cyclosporin induced; induced gingival; gingival overgrowth ... See more keywords