In‐silico structural characterization and phylogenetic analysis of Nucleoside diphosphate kinase: A novel antiapoptotic protein of Porphyromonas gingivalis
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.30389
Abstract: The Nucleoside diphosphate kinase (NDK) protein of Porphyromonas gingivalis (P. gingivalis) plays a crucial role in immune evasion and inhibition of apoptosis in host cells and has the potential to cause cancer. However, its structure… read more here.
Keywords: structure; gingivalis; nucleoside diphosphate; diphosphate kinase ... See more keywords
Inhibitory effects of azithromycin on the adherence ability of Porphyromonas gingivalis.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of periodontology"
DOI: 10.1002/jper.18-0559
Abstract: BACKGROUND Porphyromonas gingivalis is a major pathogen and has a high detection rate in periodontal disease. Fimbriae and hemagglutinin are expressed by P. gingivalis, and these play an important role in the adherence of the… read more here.
Keywords: porphyromonas gingivalis; mics azithromycin; sub mics; adherence ... See more keywords
Antimicrobial function of the polyunsaturated fatty acid ketoC in an experimental model of periodontitis.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of periodontology"
DOI: 10.1002/jper.19-0130
Abstract: BACKGROUND The bioactive metabolite KetoC, generated by intestinal bacteria, exerts various beneficial effects. Nevertheless, its function in the pathogenesis of periodontitis remains unclear. Here we investigated the effect of KetoC in a mouse model of… read more here.
Keywords: ketoc; periodontitis; model periodontitis; gingivalis ... See more keywords
Structure, function, and inhibition of a genomic/clinical variant of Porphyromonas gingivalis peptidylarginine deiminase
Sign Up to like & getrecommendations! Published in 2019 at "Protein Science"
DOI: 10.1002/pro.3571
Abstract: Citrullination is an essential post‐translational modification in which the guanidinium group of protein and peptide arginines is deiminated by peptidylarginine deiminases (PADs). When deregulated, excessive citrullination leads to inflammation as in severe periodontal disease (PD)… read more here.
Keywords: ppad; variant; porphyromonas gingivalis; gingivalis ... See more keywords
Relationship of Porphyromonas gingivalis and Alzheimer's disease: a systematic review of pre-clinical studies.
Sign Up to like & getrecommendations! Published in 2021 at "Clinical oral investigations"
DOI: 10.1007/s00784-020-03764-w
Abstract: OBJECTIVES This study aimed to analyze the following PICO question: Are animals infected with Porphyromonas gingivalis (P. gingivalis) or bacterial lipopolysaccharide (Pg-LPS) more affected by neurodegeneration, similar to the pathogenesis generated by Alzheimer's disease (AD), compared… read more here.
Keywords: alzheimer disease; porphyromonas gingivalis; disease; gingivalis ... See more keywords
Antimicrobial effect of photodynamic therapy using sinoporphyrin sodium and 390–400 nm light-emitting diode on Porphyromonas gingivalis in vitro
Sign Up to like & getrecommendations! Published in 2020 at "Lasers in Medical Science"
DOI: 10.1007/s10103-020-03067-2
Abstract: This study aims to investigate the effect of antimicrobial photodynamic therapy (a-PDT) using a novel combination of sinoporphyrin sodium (DVDMS) and light-emitting diode (LED) with a wavelength of 390–400 nm on Porphyromonas gingivalis in vitro. Absorption… read more here.
Keywords: photodynamic therapy; gingivalis; effect; 400 led ... See more keywords
Enhanced Responsive Formation of Extracellular Traps in Macrophages Previously Exposed to Porphyromonas gingivalis
Sign Up to like & getrecommendations! Published in 2022 at "Inflammation"
DOI: 10.1007/s10753-021-01611-y
Abstract: Tolerance is defined to be a hyporesponsive state following repeated stimulations with bacteria or their virulence factors and has potential impacts on the development of periodontitis. Recently, macrophages have been reported to release chromatin and… read more here.
Keywords: gingivalis; microscopy; gingivalis pretreated; pretreated macrophages ... See more keywords
Current Global Status and the Epidemiology of Entamoeba gingivalis in Humans: A Systematic Review and Meta-analysis.
Sign Up to like & getrecommendations! Published in 2021 at "Acta parasitologica"
DOI: 10.1007/s11686-021-00423-2
Abstract: PURPOSE Entamoeba gingivalis (E. gingivalis) is one of the members of the wide range of oral resident pathogens in humans, particularly found in dental plaques, surfaces of gingiva or teeth, interdental spaces and carious lesions.… read more here.
Keywords: review meta; infection; prevalence; gingivalis ... See more keywords
Relatively low invasive capacity of Porphyromonas gingivalis strains into human gingival fibroblasts in vitro.
Sign Up to like & getrecommendations! Published in 2017 at "Archives of oral biology"
DOI: 10.1016/j.archoralbio.2017.08.007
Abstract: OBJECTIVE Bacterial invasion into host cells is a common strategy to escape the host immune system. Gingival fibroblasts (GFs) are the most predominant non-phagocytic cell type in gingival connective tissue. Therefore, invasion into GFs was… read more here.
Keywords: invasive ability; invasion; gfs; gingivalis ... See more keywords
Doxycycline inhibits NAcht Leucine-rich repeat Protein 3 inflammasome activation and interleukin-1β production induced by Porphyromonas gingivalis-lipopolysaccharide and adenosine triphosphate in human gingival fibroblasts.
Sign Up to like & getrecommendations! Published in 2019 at "Archives of oral biology"
DOI: 10.1016/j.archoralbio.2019.104514
Abstract: OBJECTIVE To investigate the effect of adenosine triphosphate (ATP) on inflammasome activation by Porphyromonas gingivalis-lipopolysaccharide (P. gingivalis-LPS) stimulation and the anti-inflammatory eff ;ect of doxycycline (Dox) in human gingival fibroblasts (HGFs). DESIGN The optimal concentration… read more here.
Keywords: protein; production; adenosine triphosphate; gingivalis ... See more keywords
Effect of probiotic Lactobacillus rhamnosus by-products on gingival epithelial cells challenged with Porphyromonas gingivalis.
Sign Up to like & getrecommendations! Published in 2021 at "Archives of oral biology"
DOI: 10.1016/j.archoralbio.2021.105174
Abstract: OBJECTIVE Probiotics are usually given as living cells, but their effects may be also achieved by postbiotics. We hypothesized that probiotics products (spent media and lysate) altered the response induced by P. gingivalis in gingival… read more here.
Keywords: epithelial cells; gingival epithelial; inflammatory mediators; gingivalis ... See more keywords