Porphyromonas gingivalis Infection Upregulates the Endothelin (ET) System in Brain Microvascular Endothelial Cells.
Sign Up to like & getrecommendations! Published in 2022 at "Canadian journal of physiology and pharmacology"
DOI: 10.1139/cjpp-2022-0035
Abstract: Endothelin-1 (ET-1), the most potent vasoconstrictor identified to date, contributes to cerebrovascular dysfunction and brain ET-1 levels were shown to be related to ADRD progression. ET-1 also contributes to neuroinflammation, especially in infections of the… read more here.
Keywords: system; brain microvascular; infection; porphyromonas gingivalis ... See more keywords
P. gingivalis Infection Upregulates PD-L1 Expression on Dendritic Cells, Suppresses CD8+ T-cell Responses, and Aggravates Oral Cancer
Sign Up to like & getrecommendations! Published in 2023 at "Cancer Immunology Research"
DOI: 10.1158/2326-6066.cir-22-0541
Abstract: Immunosuppressive properties of the oral anaerobic bacterium Porphyromonas gingivalis are revealed, highlighting effects of the bacterium that facilitate oral cancer progression. The data suggest that P. gingivalis, and/or signaling it mediates, can be targeted to… read more here.
Keywords: upregulates expression; infection upregulates; oral cancer; gingivalis ... See more keywords