Stem cells rescue cardiomyopathy induced by P. gingivalis‐LPS via miR‐181b
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.26386
Abstract: Systemic inflammation induced by bacterial infection is one of several causative agents for cardiovascular disorders in patients with periodontal disease. Experimental results indicate that miRNAs play important roles in systemic inflammation induced by endotoxins. Further… read more here.
Keywords: cardiomyopathy induced; gingivalis lps; h9c2 nrcms; stem cells ... See more keywords
Effects of Endotoxin Tolerance Induced by Porphyromonas gingivalis Lipopolysaccharide on Inflammatory Responses in Neutrophils
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DOI: 10.1007/s10753-020-01243-8
Abstract: Periodontitis is a dental plaque–induced chronic inflammatory disease. Long-term exposure of the host to periodontal pathogens leads to a hyporesponsive state to the following stimulations, which is described as endotoxin tolerance. Neutrophils are the most… read more here.
Keywords: inflammatory responses; tolerance; gingivalis lps; tolerized neutrophils ... See more keywords
Doxycycline inhibits NAcht Leucine-rich repeat Protein 3 inflammasome activation and interleukin-1β production induced by Porphyromonas gingivalis-lipopolysaccharide and adenosine triphosphate in human gingival fibroblasts.
Sign Up to like & getrecommendations! Published in 2019 at "Archives of oral biology"
DOI: 10.1016/j.archoralbio.2019.104514
Abstract: OBJECTIVE To investigate the effect of adenosine triphosphate (ATP) on inflammasome activation by Porphyromonas gingivalis-lipopolysaccharide (P. gingivalis-LPS) stimulation and the anti-inflammatory eff ;ect of doxycycline (Dox) in human gingival fibroblasts (HGFs). DESIGN The optimal concentration… read more here.
Keywords: protein; production; adenosine triphosphate; gingivalis ... See more keywords
Porphyromonas gingivalis lipopolysaccharide affects oral epithelial connections via pyroptosis
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Dental Sciences"
DOI: 10.1016/j.jds.2021.01.003
Abstract: Background/purpose Pyroptosis is a form of programmed cell death dependent on the activation of caspase-1. Porphyromonas gingivalis (P. gingivalis) is a major pathogenic bacterium in periodontitis and its lipopolysaccharide (LPS) can trigger inflammation. However, whether… read more here.
Keywords: caspase; pyroptosis; porphyromonas gingivalis; gingivalis ... See more keywords
Porphyromonas gingivalis lipopolysaccharide induces cognitive dysfunction, mediated by neuronal inflammation via activation of the TLR4 signaling pathway in C57BL/6 mice
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Neuroinflammation"
DOI: 10.1186/s12974-017-1052-x
Abstract: BackgroundPorphyromonas gingivalis lipopolysaccharide (P. gingivalis-LPS) is one of the major pathogenic factors of chronic periodontitis (CP). Few reports on the correlation between P. gingivalis-LPS and cognitive function exist. Thus, the present study aimed to investigate… read more here.
Keywords: c57bl mice; signaling pathway; gingivalis lps; mice ... See more keywords
3LPS-binding protein and its interactions with P. gingivalis LPS modulate pro-inflammatory response and Toll-like receptor signaling in human oral keratinocytes
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DOI: 10.1371/journal.pone.0173223
Abstract: Lipopolysaccharide (LPS)-binding protein (LBP) as an acute-phase protein plays a crucial role in innate host response to bacterial challenge. Our previous study shows that LBP expression in human gingiva is associated with periodontal status. Porphyromonas… read more here.
Keywords: lps1435 1449; gingivalis lps; expression; binding protein ... See more keywords
P. gingivalis-LPS Induces Mitochondrial Dysfunction Mediated by Neuroinflammation through Oxidative Stress
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24020950
Abstract: Porphyromonas gingivalis (P. gingivalis), a key pathogen in periodontitis, is associated with neuroinflammation. Periodontal disease increases with age; 70.1% of adults 65 years and older have periodontal problems. However, the P. gingivalis- lipopolysaccharide (LPS)induced mitochondrial… read more here.
Keywords: mitochondrial dysfunction; gingivalis lps; neuroinflammation; oxidative stress ... See more keywords
The Effect of Cyanobacterial LPS Antagonist (CyP) on Cytokines and Micro-RNA Expression Induced by Porphyromonas gingivalis LPS
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DOI: 10.3390/toxins10070290
Abstract: Lipopolysaccharide (LPS) from Porphyromonas gingivalis (Pg-LPS) is a key bacterial structure involved in the maintenance of a chronic pro-inflammatory environment during periodontitis. Similar to other gram-negative LPS, Pg-LPS induces the release of pro-inflammatory cytokines through… read more here.
Keywords: lps; porphyromonas gingivalis; gingivalis lps; expression ... See more keywords