Paenibacillus roseus sp. nov., a ginsenoside-transforming bacterium isolated from forest soil.
Sign Up to like & getrecommendations! Published in 2021 at "Archives of microbiology"
DOI: 10.1007/s00203-021-02389-1
Abstract: A novel, pink-pigmented, Gram-stain-positive, aerobic, motile, rod-shaped and ginsenoside-converting bacterium, designated strain MAHUQ-46T, was isolated from soil of a forest. Strain MAHUQ-46T grew in the pH range 6.0-9.0 (optimum, 7.5), at temperatures between 10 and… read more here.
Keywords: strain mahuq; roseus nov; ginsenoside; paenibacillus roseus ... See more keywords
Identification of two UDP-glycosyltransferases involved in the main oleanane-type ginsenosides in Panax japonicus var. major.
Sign Up to like & getrecommendations! Published in 2021 at "Planta"
DOI: 10.1007/s00425-021-03617-0
Abstract: MAIN CONCLUSION Two UDP-glycosyltransferases from Panax japonicus var. major were identified, and the biosynthetic pathways of three oleanane-type ginsenosides (chikusetsusaponin IVa, ginsenoside Ro, zingibroside R1) were elucidated. Chikusetsusaponin IVa and ginsenoside Ro are primary active… read more here.
Keywords: iva ginsenoside; ginsenoside; udp glycosyltransferases; japonicus var ... See more keywords
Facile reduction and stabilization of ginsenoside-functionalized gold nanoparticles: optimization, characterization, and in vitro cytotoxicity studies
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Nanoparticle Research"
DOI: 10.1007/s11051-017-3980-x
Abstract: AbstractGold nanoparticles (GNPs) are forecasted to provide an attractive platform in biomedicine and catalysis with their potentials of combining a variety of biophysicochemical properties into an integrated nanodevice with great therapeutic and optical functions. There… read more here.
Keywords: reduction; reduction stabilization; ginsenoside; stabilization ginsenoside ... See more keywords
Enhanced Production of Protopanaxatriol from Ginsenoside Re and Rg1 Using a Recombinant Bacterial β-glucosidase
Sign Up to like & getrecommendations! Published in 2019 at "Biotechnology and Bioprocess Engineering"
DOI: 10.1007/s12257-019-0090-x
Abstract: 20(S)-protopanaxatriol (PPTA), an aglycone of ginseng saponins, is rarely found and is present in a limited amount; it exhibits various pharmaceutical activities, including memory improvement, and anti-diabetic and anti-cancer effects. An enzymatic method was developed… read more here.
Keywords: production; ginsenoside; using recombinant; protopanaxatriol ... See more keywords
Pharmacokinetics of ginsenosides following repeated oral administration of red ginseng extract significantly differ between species of experimental animals.
Sign Up to like & getrecommendations! Published in 2020 at "Archives of pharmacal research"
DOI: 10.1007/s12272-020-01289-0
Abstract: We aimed to investigate ginsenoside pharmacokinetics in mice and rats following the repeated oral administration of red ginseng extract (RGE) (2 g/kg/day for 7 days). In mouse plasma, seven protopanaxadiol (PPD)-type ginsenosides (20(S)-ginsenoside Rb1, Rb2, Rc, Rd,… read more here.
Keywords: ginsenoside; red ginseng; following repeated; oral administration ... See more keywords
Cloning, overexpression and characterization of a thermostable β-xylosidase from Thermotoga petrophila and cooperated transformation of ginsenoside extract to ginsenoside 20(S)-Rg3 with a β-glucosidase.
Sign Up to like & getrecommendations! Published in 2019 at "Bioorganic chemistry"
DOI: 10.1016/j.bioorg.2018.12.026
Abstract: A thermostable β-xylosidase gene Tpexyl3 from Thermotoga petrophila DSM 13,995 was cloned and overexpressed by Escherichia coli. Recombinant Tpexyl3 was purified, and its molecular weight was approximately 86.7 kDa. Its optimal activity was exhibited at pH… read more here.
Keywords: ginsenoside; thermotoga petrophila; ginsenoside extract; rg3 ... See more keywords
Enzymatic hydrolysis and extraction of ginsenoside recovered from deep eutectic solvent-salt aqueous two-phase system.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of bioscience and bioengineering"
DOI: 10.1016/j.jbiosc.2020.05.008
Abstract: Rare ginsenoside CK was recognized as a popular functional food because of superior pharmacological activity, but it is restricted by further applications by the difficulty in preparation. In this study, deep eutectic solvent (DES)-based aqueous… read more here.
Keywords: phase; ginsenoside; two phase; deep eutectic ... See more keywords
Remarkable impact of steam temperature on ginsenosides transformation from fresh ginseng to red ginseng
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Ginseng Research"
DOI: 10.1016/j.jgr.2017.02.003
Abstract: Background Temperature is an essential condition in red ginseng processing. The pharmacological activities of red ginseng under different steam temperatures are significantly different. Methods In this study, an ultrahigh-performance liquid chromatography quadrupole time-of-flight tandem mass… read more here.
Keywords: temperature; ginsenoside; ginseng; ginseng steamed ... See more keywords
Recent Advances in Yeast Recombinant Biosynthesis of the Triterpenoid Protopanaxadiol and Glycosylated Derivatives Thereof.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of agricultural and food chemistry"
DOI: 10.1021/acs.jafc.2c06888
Abstract: Plant natural products are a seemingly endless resource for novel chemical structures. However, their extraction often results in high prices, fluctuation in both quantity and quality, and negative environmental impact. The latter might result from… read more here.
Keywords: biosynthesis; ginsenoside; biology; advances yeast ... See more keywords
Combinatorial Enzymatic Catalysis for Bioproduction of Ginsenoside Compound K.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of agricultural and food chemistry"
DOI: 10.1021/acs.jafc.2c08773
Abstract: Ginsenoside compound K (CK) is an emerging functional food or pharmaceutical product. To date, there are still challenges to exploring effective catalytic enzymes for enzyme-catalyzed manufacturing processes and establishing enzyme-catalyzed processes. Herein, we identified three… read more here.
Keywords: enzyme catalyzed; ginsenoside; ginsenoside compound; enzymatic catalysis ... See more keywords
Ginsenoside CK Alleviates DSS-Induced IBD in Mice by Regulating Tryptophan Metabolism and Activating Aryl Hydrocarbon Receptor via Gut Microbiota Modulation.
Sign Up to like & getrecommendations! Published in 2024 at "Journal of agricultural and food chemistry"
DOI: 10.1021/acs.jafc.4c00245
Abstract: Dysbiosis of gut microbiota is believed to be associated with inflammatory bowel disease (IBD). Ginsenoside compound K (CK), the main metabolite of Panax ginseng ginsenoside, has proven effective as an anti-inflammatory agent in IBD. However,… read more here.
Keywords: ibd; gut microbiota; gut; aryl hydrocarbon ... See more keywords